Wogonin suppresses stem cell-like traits of CD133 positive osteosarcoma cell via inhibiting matrix metallopeptidase-9 expression

Wogonin suppresses stem cell-like traits of CD133 positive osteosarcoma cell via inhibiting matrix metallopeptidase-9 expression

Abstract Background Several efforts have been deployed to cure osteosarcoma, a high-grade malignant bone tumour in children and adolescents. However, some challenges such as drug resistance, relapse, and tumour metastasis remain owing to the existence of cancer stem cells (CSC). There is an urgent n...

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Bibliographic Details
Main Authors: Do Luong Huynh, Taeho Kwon, Jiao Jiao Zhang, Neelesh Sharma, Meeta Gera, Mrinmoy Ghosh, Nameun Kim, Somi Kim Cho, Dong Sun Lee, Yang Ho Park, Dong Kee Jeong
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Wogonin
Scutellaria baicalensis
Osteosarcoma
Cancer stem cells
Mobility
Online Access:http://link.springer.com/article/10.1186/s12906-017-1788-y

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