Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)

The use of magnesium preparations in medicine has a long history. According to some sources, first attempts by humans to consume magnesium- and calcium-rich minerals orally, presumably for medicinal purposes, could have occurred even in prehistoric times. First attempts to use natural magnesium-calc...

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Main Authors: A. R. Bekker, Yu. V. Bykov, A. O. Shkurat, A. S. Voronina
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2019-07-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/2087
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author A. R. Bekker
Yu. V. Bykov
A. O. Shkurat
A. S. Voronina
author_facet A. R. Bekker
Yu. V. Bykov
A. O. Shkurat
A. S. Voronina
author_sort A. R. Bekker
collection DOAJ
description The use of magnesium preparations in medicine has a long history. According to some sources, first attempts by humans to consume magnesium- and calcium-rich minerals orally, presumably for medicinal purposes, could have occurred even in prehistoric times. First attempts to use natural magnesium-calcium alkaline materials to increase the bioavailability of the alkaloids of some psychoactive plants, such as betel, tobacco, and coca, also date back to prehistoric times.Later, several ancient authors, in particular, Hippocrates II, Claudius Galen and Soran of Ephesus, have described the profound laxative effect of sea salt and of crushed dolomite, as well as a positive effect on the psyche of drinking mineral waters from sources that were found by modern scientists to be rich in magnesium, lithium and bromine. The laxative effect of mineral waters from some sources rich in magnesium, or of salts that were extracted from such sources was known in the Middle Ages. Later, Paracelsus discovered that these salts could be useful not only as a laxative, but also as a sedative.In 1707, Massimiliano Valentini first obtained magnesium oxide, which immediately found its use in medicine, as an antacid, as a mild laxative and skin powder. In 1926, Jacques Leroy was the first to prove the vital importance of magnesium for the physiology of animals.In this article, we thoroughly review the history of the medicinal use of magnesium preparations and the history of studies of biological role of magnesium, from antiquity to modern times.
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spelling doaj.art-c619d2f80d5a41708d4f437591a26bfa2024-03-28T07:49:21ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962019-07-0143638010.29413/ABS.2019-4.3.91884Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)A. R. Bekker0Yu. V. Bykov1A. O. Shkurat2A. S. Voronina3Ben-Gurion University of the NegevStavropol State Medical UniversityYaroslavl State Medical UniversityYaroslavl State Medical UniversityThe use of magnesium preparations in medicine has a long history. According to some sources, first attempts by humans to consume magnesium- and calcium-rich minerals orally, presumably for medicinal purposes, could have occurred even in prehistoric times. First attempts to use natural magnesium-calcium alkaline materials to increase the bioavailability of the alkaloids of some psychoactive plants, such as betel, tobacco, and coca, also date back to prehistoric times.Later, several ancient authors, in particular, Hippocrates II, Claudius Galen and Soran of Ephesus, have described the profound laxative effect of sea salt and of crushed dolomite, as well as a positive effect on the psyche of drinking mineral waters from sources that were found by modern scientists to be rich in magnesium, lithium and bromine. The laxative effect of mineral waters from some sources rich in magnesium, or of salts that were extracted from such sources was known in the Middle Ages. Later, Paracelsus discovered that these salts could be useful not only as a laxative, but also as a sedative.In 1707, Massimiliano Valentini first obtained magnesium oxide, which immediately found its use in medicine, as an antacid, as a mild laxative and skin powder. In 1926, Jacques Leroy was the first to prove the vital importance of magnesium for the physiology of animals.In this article, we thoroughly review the history of the medicinal use of magnesium preparations and the history of studies of biological role of magnesium, from antiquity to modern times.https://www.actabiomedica.ru/jour/article/view/2087magnesiumcalciumlithiumbromidehistory of medicinetetanyepilepsyspasmophiliahumoral theory
spellingShingle A. R. Bekker
Yu. V. Bykov
A. O. Shkurat
A. S. Voronina
Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)
Acta Biomedica Scientifica
magnesium
calcium
lithium
bromide
history of medicine
tetany
epilepsy
spasmophilia
humoral theory
title Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)
title_full Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)
title_fullStr Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)
title_full_unstemmed Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)
title_short Magnesium Preparations in Psychiatry, Addiction Medicine, Neurology and General Medicine (Part I. History)
title_sort magnesium preparations in psychiatry addiction medicine neurology and general medicine part i history
topic magnesium
calcium
lithium
bromide
history of medicine
tetany
epilepsy
spasmophilia
humoral theory
url https://www.actabiomedica.ru/jour/article/view/2087
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AT yuvbykov magnesiumpreparationsinpsychiatryaddictionmedicineneurologyandgeneralmedicinepartihistory
AT aoshkurat magnesiumpreparationsinpsychiatryaddictionmedicineneurologyandgeneralmedicinepartihistory
AT asvoronina magnesiumpreparationsinpsychiatryaddictionmedicineneurologyandgeneralmedicinepartihistory