Response Facilitation Induced by Insulin-like Growth Factor-I in the Primary Somatosensory Cortex of Mice Was Reduced in Aging

Response Facilitation Induced by Insulin-like Growth Factor-I in the Primary Somatosensory Cortex of Mice Was Reduced in Aging

Aging is accompanied by a decline in cognition that can be due to a lower IGF-I level. We studied response facilitation induced in primary somatosensory (S1) cortical neurons by repetitive stimulation of whiskers in young and old mice. Layer 2/3 and 5/6 neurons were extracellularly recorded in young...

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Bibliographic Details
Main Authors: Nuria García-Magro, Jonathan A. Zegarra-Valdivia, Sara Troyas-Martinez, Ignacio Torres-Aleman, Angel Nuñez
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
S1 cortex
IGF-I
IGF-I receptors
response facilitation
aging
Online Access:https://www.mdpi.com/2073-4409/11/4/717

Internet

https://www.mdpi.com/2073-4409/11/4/717

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