Paraquat is an agonist of STIM1 and increases intracellular calcium levels
The herbicide paraquat is an agonist of Stromal Interaction Molecule 1 (STIM1), leading to extracellular calcium entry observed in epithelial-mesenchymal transition in alveolar cells during pulmonary fibrosis.
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04130-0 |
| _version_ | 1797991775700254720 |
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| author | Wenyu Yang Rui Tian Yong Zhu Peijie Huang Xinrun Ma Xiaoxiao Meng Wentao Dai Yiming Tao Daonan Chen Jiaxiang Zhang Jian Lu Hui Xie Xiangdong Jian Zhengfeng Yang Ruilan Wang |
| author_facet | Wenyu Yang Rui Tian Yong Zhu Peijie Huang Xinrun Ma Xiaoxiao Meng Wentao Dai Yiming Tao Daonan Chen Jiaxiang Zhang Jian Lu Hui Xie Xiangdong Jian Zhengfeng Yang Ruilan Wang |
| author_sort | Wenyu Yang |
| collection | DOAJ |
| description | The herbicide paraquat is an agonist of Stromal Interaction Molecule 1 (STIM1), leading to extracellular calcium entry observed in epithelial-mesenchymal transition in alveolar cells during pulmonary fibrosis. |
| first_indexed | 2024-04-11T08:57:39Z |
| format | Article |
| id | doaj.art-c61f1911378e4ceab97837bb0f4bd421 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-11T08:57:39Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-c61f1911378e4ceab97837bb0f4bd4212022-12-22T04:33:09ZengNature PortfolioCommunications Biology2399-36422022-10-015111110.1038/s42003-022-04130-0Paraquat is an agonist of STIM1 and increases intracellular calcium levelsWenyu Yang0Rui Tian1Yong Zhu2Peijie Huang3Xinrun Ma4Xiaoxiao Meng5Wentao Dai6Yiming Tao7Daonan Chen8Jiaxiang Zhang9Jian Lu10Hui Xie11Xiangdong Jian12Zhengfeng Yang13Ruilan Wang14Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicinePrecision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineShanghai Center for Bioinformation Technology, Shanghai Academy of Science and TechnologyDepartment of Poisoning and Occupational Diseases, Emergency, Qilu Hospital, Cheeloo College of Medicine, Shandong UniversityDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Poisoning and Occupational Diseases, Emergency, Qilu Hospital, Cheeloo College of Medicine, Shandong UniversityDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of MedicineThe herbicide paraquat is an agonist of Stromal Interaction Molecule 1 (STIM1), leading to extracellular calcium entry observed in epithelial-mesenchymal transition in alveolar cells during pulmonary fibrosis.https://doi.org/10.1038/s42003-022-04130-0 |
| spellingShingle | Wenyu Yang Rui Tian Yong Zhu Peijie Huang Xinrun Ma Xiaoxiao Meng Wentao Dai Yiming Tao Daonan Chen Jiaxiang Zhang Jian Lu Hui Xie Xiangdong Jian Zhengfeng Yang Ruilan Wang Paraquat is an agonist of STIM1 and increases intracellular calcium levels Communications Biology |
| title | Paraquat is an agonist of STIM1 and increases intracellular calcium levels |
| title_full | Paraquat is an agonist of STIM1 and increases intracellular calcium levels |
| title_fullStr | Paraquat is an agonist of STIM1 and increases intracellular calcium levels |
| title_full_unstemmed | Paraquat is an agonist of STIM1 and increases intracellular calcium levels |
| title_short | Paraquat is an agonist of STIM1 and increases intracellular calcium levels |
| title_sort | paraquat is an agonist of stim1 and increases intracellular calcium levels |
| url | https://doi.org/10.1038/s42003-022-04130-0 |
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