GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTS
<p>Glucocorticoids (GCs) are first-line drugs to treat systemic lupus erythematosus (SLE) of both high and moderate activities. These are the only agents that are able to provide so prompt anti-inflammatory and immunosuppressant effects in rheumatic diseases. Along with antimalarials and immun...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2014-11-01
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| Series: | Klinicist |
| Subjects: | |
| Online Access: | http://klinitsist.abvpress.ru/index.php/Klin/article/view/150 |
| _version_ | 1797971786319527936 |
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| author | N. V. Seredavkina A. V. Smirnov I. S. Dydykina T. M. Reshetnyak |
| author_facet | N. V. Seredavkina A. V. Smirnov I. S. Dydykina T. M. Reshetnyak |
| author_sort | N. V. Seredavkina |
| collection | DOAJ |
| description | <p>Glucocorticoids (GCs) are first-line drugs to treat systemic lupus erythematosus (SLE) of both high and moderate activities. These are the only agents that are able to provide so prompt anti-inflammatory and immunosuppressant effects in rheumatic diseases. Along with antimalarials and immunosuppressants, GCs are used in the standard classical treatment regimen for SLE; however, despite the high efficacy of these drugs, their related immediate or delayed adverse reactions are one of the major problems in the management of a patient with SLE. Occasionally, they may be severer than the indication itself for their use and may be even fatal. The paper describes the adverse reactions observed in a female patient with SLE during long-term use of a high maintenance GC dose.</p> |
| first_indexed | 2024-04-11T03:38:07Z |
| format | Article |
| id | doaj.art-c6213d0af50e4aa8822591143090b719 |
| institution | Directory Open Access Journal |
| issn | 1818-8338 |
| language | Russian |
| last_indexed | 2024-04-11T03:38:07Z |
| publishDate | 2014-11-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Klinicist |
| spelling | doaj.art-c6213d0af50e4aa8822591143090b7192023-01-02T04:44:18ZrusABV-pressKlinicist1818-83382014-11-01816370165GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTSN. V. Seredavkina0A. V. Smirnov1I. S. Dydykina2T. M. Reshetnyak3V. A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, MoscowV. A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, MoscowV. A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, MoscowV. A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow<p>Glucocorticoids (GCs) are first-line drugs to treat systemic lupus erythematosus (SLE) of both high and moderate activities. These are the only agents that are able to provide so prompt anti-inflammatory and immunosuppressant effects in rheumatic diseases. Along with antimalarials and immunosuppressants, GCs are used in the standard classical treatment regimen for SLE; however, despite the high efficacy of these drugs, their related immediate or delayed adverse reactions are one of the major problems in the management of a patient with SLE. Occasionally, they may be severer than the indication itself for their use and may be even fatal. The paper describes the adverse reactions observed in a female patient with SLE during long-term use of a high maintenance GC dose.</p>http://klinitsist.abvpress.ru/index.php/Klin/article/view/150glucocorticoidsside effectssystemic lupus erythematosus |
| spellingShingle | N. V. Seredavkina A. V. Smirnov I. S. Dydykina T. M. Reshetnyak GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTS Klinicist glucocorticoids side effects systemic lupus erythematosus |
| title | GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTS |
| title_full | GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTS |
| title_fullStr | GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTS |
| title_full_unstemmed | GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTS |
| title_short | GLUCOCORTICOIDS IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS: POSITIVE AND NEGATIVE ASPECTS |
| title_sort | glucocorticoids in the treatment of systemic lupus erythematosus positive and negative aspects |
| topic | glucocorticoids side effects systemic lupus erythematosus |
| url | http://klinitsist.abvpress.ru/index.php/Klin/article/view/150 |
| work_keys_str_mv | AT nvseredavkina glucocorticoidsinthetreatmentofsystemiclupuserythematosuspositiveandnegativeaspects AT avsmirnov glucocorticoidsinthetreatmentofsystemiclupuserythematosuspositiveandnegativeaspects AT isdydykina glucocorticoidsinthetreatmentofsystemiclupuserythematosuspositiveandnegativeaspects AT tmreshetnyak glucocorticoidsinthetreatmentofsystemiclupuserythematosuspositiveandnegativeaspects |