Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study
Fang Yu,1,* Aizhong Liu,2,* Zhiming Deng,1,* Shenglian Gan,1 Quan Zhou,3 Haowen Long4 1Department of Endocrinology, The First People’s Hospital of Changde City, Changde, Hunan, People’s Republic of China; 2Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya Scho...
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Dove Medical Press
2023-06-01
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| Series: | International Journal of General Medicine |
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| Online Access: | https://www.dovepress.com/association-between-chinese-visceral-adipose-index-and-albuminuria-in--peer-reviewed-fulltext-article-IJGM |
| _version_ | 1797810006666510336 |
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| author | Yu F Liu A Deng Z Gan S Zhou Q Long H |
| author_facet | Yu F Liu A Deng Z Gan S Zhou Q Long H |
| author_sort | Yu F |
| collection | DOAJ |
| description | Fang Yu,1,* Aizhong Liu,2,* Zhiming Deng,1,* Shenglian Gan,1 Quan Zhou,3 Haowen Long4 1Department of Endocrinology, The First People’s Hospital of Changde City, Changde, Hunan, People’s Republic of China; 2Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha, Hunan, People’s Republic of China; 3Department of Science and Education Section, The First People’s Hospital of Changde City, Changde, Hunan, People’s Republic of China; 4Department of Radiology, The First People’s Hospital of Changde City, Changde, Hunan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiming Deng, Department of Endocrinology, The First People’s Hospital of Changde City, 818 Renmin Road, Changde, Hunan, 415000, People’s Republic of China, Tel +86 736-7788026, Email 13974221766@163.comPurpose: To explore the correlation between Chinese visceral adipose index (CVAI) and urinary microalbumin/creatinine ratio (UACR) and urinary albumin, and whether there is any difference in correlation between Han and Tujia ethnicity.Methods: This cross-sectional study was conducted in Changde, Hunan, China from May 2021 to December 2021. Biochemical indicators including anthropometric parameters, blood pressure, blood glucose, blood lipids, and UACR of the participants were measured. Univariate analysis, multivariate analyses and multinomial logistic regression analysis were carried out to assess the association between CVAI and albuminuria. In addition, curve fitting and threshold effect analysis were used to explore the nonlinear association between CVAI and albuminuria, and to observe whether there were ethnic differences in this association.Results: A total of 2026 adult residents were enrolled in this study, 500 of whom had albuminuria. Population-standardized prevalence of albuminuria is 19.06%. In the multivariable model adjusted for confounding factors, the odds ratio (OR) of albuminuria for pre-unit increase of CVAI and pre-SD increase of CVAI were 1.007 (1.003– 1.010) and 1.298 (1.127– 1.496), respectively. Multinomial logistic regression analysis confirmed the robustness and consistency of the results.The generalized additive model showed that CVAI and albuminuria had a nonlinear relationship with inflection point at 97.201 using the threshold effect. Compared with Han ethnic groups, the threshold between CVAI and albuminuria in Tujia people moved backward. The thresholds were 159.785 and 98.527, respectively.Conclusion: There was a positive nonlinear dose-response relationship between increased CVAI and higher levels of albuminuria. Maintaining appropriate CVAI levels may be important for the prevention of albuminuria.Keywords: Chinese visceral adipose index, urinary microalbumin to creatinine ratio, albuminuria, obesity |
| first_indexed | 2024-03-13T07:01:34Z |
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| last_indexed | 2024-03-13T07:01:34Z |
| publishDate | 2023-06-01 |
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| spelling | doaj.art-c62214c0dc7e47a19c4a1dac9aa943752023-06-06T19:22:44ZengDove Medical PressInternational Journal of General Medicine1178-70742023-06-01Volume 162271228384229Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional StudyYu FLiu ADeng ZGan SZhou QLong HFang Yu,1,* Aizhong Liu,2,* Zhiming Deng,1,* Shenglian Gan,1 Quan Zhou,3 Haowen Long4 1Department of Endocrinology, The First People’s Hospital of Changde City, Changde, Hunan, People’s Republic of China; 2Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha, Hunan, People’s Republic of China; 3Department of Science and Education Section, The First People’s Hospital of Changde City, Changde, Hunan, People’s Republic of China; 4Department of Radiology, The First People’s Hospital of Changde City, Changde, Hunan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiming Deng, Department of Endocrinology, The First People’s Hospital of Changde City, 818 Renmin Road, Changde, Hunan, 415000, People’s Republic of China, Tel +86 736-7788026, Email 13974221766@163.comPurpose: To explore the correlation between Chinese visceral adipose index (CVAI) and urinary microalbumin/creatinine ratio (UACR) and urinary albumin, and whether there is any difference in correlation between Han and Tujia ethnicity.Methods: This cross-sectional study was conducted in Changde, Hunan, China from May 2021 to December 2021. Biochemical indicators including anthropometric parameters, blood pressure, blood glucose, blood lipids, and UACR of the participants were measured. Univariate analysis, multivariate analyses and multinomial logistic regression analysis were carried out to assess the association between CVAI and albuminuria. In addition, curve fitting and threshold effect analysis were used to explore the nonlinear association between CVAI and albuminuria, and to observe whether there were ethnic differences in this association.Results: A total of 2026 adult residents were enrolled in this study, 500 of whom had albuminuria. Population-standardized prevalence of albuminuria is 19.06%. In the multivariable model adjusted for confounding factors, the odds ratio (OR) of albuminuria for pre-unit increase of CVAI and pre-SD increase of CVAI were 1.007 (1.003– 1.010) and 1.298 (1.127– 1.496), respectively. Multinomial logistic regression analysis confirmed the robustness and consistency of the results.The generalized additive model showed that CVAI and albuminuria had a nonlinear relationship with inflection point at 97.201 using the threshold effect. Compared with Han ethnic groups, the threshold between CVAI and albuminuria in Tujia people moved backward. The thresholds were 159.785 and 98.527, respectively.Conclusion: There was a positive nonlinear dose-response relationship between increased CVAI and higher levels of albuminuria. Maintaining appropriate CVAI levels may be important for the prevention of albuminuria.Keywords: Chinese visceral adipose index, urinary microalbumin to creatinine ratio, albuminuria, obesityhttps://www.dovepress.com/association-between-chinese-visceral-adipose-index-and-albuminuria-in--peer-reviewed-fulltext-article-IJGMchinese visceral adipose indexurinary microalbumin to creatinine ratioalbuminuriaobesity |
| spellingShingle | Yu F Liu A Deng Z Gan S Zhou Q Long H Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study International Journal of General Medicine chinese visceral adipose index urinary microalbumin to creatinine ratio albuminuria obesity |
| title | Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study |
| title_full | Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study |
| title_fullStr | Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study |
| title_full_unstemmed | Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study |
| title_short | Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study |
| title_sort | association between chinese visceral adipose index and albuminuria in chinese adults a cross sectional study |
| topic | chinese visceral adipose index urinary microalbumin to creatinine ratio albuminuria obesity |
| url | https://www.dovepress.com/association-between-chinese-visceral-adipose-index-and-albuminuria-in--peer-reviewed-fulltext-article-IJGM |
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