Bilateral Nocardia Keratitis after Photorefractive Keratectomy

Purpose: To report the clinical, confocal scan, and histopathologic features of Nocardia keratitis in a patient who developed bilateral infection following photorefractive keratectomy (PRK). Case Report: A 23-year-old woman underwent bilateral PRK for low myopia. On postoperative day 3, dense centr...

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Main Authors: Amir Faramarzi, Sepehr Feizi, Mohammad-Ali Javadi, Mozhgan Rezaei Kanavi, Forouzan Yazdizadeh, Hamid-Reza Moein
Format: Article
Language:English
Published: Knowledge E 2012-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2012;volume=7;issue=2;spage=162;epage=166;aulast=Faramarzi
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author Amir Faramarzi
Sepehr Feizi
Mohammad-Ali Javadi
Mozhgan Rezaei Kanavi
Forouzan Yazdizadeh
Hamid-Reza Moein
author_facet Amir Faramarzi
Sepehr Feizi
Mohammad-Ali Javadi
Mozhgan Rezaei Kanavi
Forouzan Yazdizadeh
Hamid-Reza Moein
author_sort Amir Faramarzi
collection DOAJ
description Purpose: To report the clinical, confocal scan, and histopathologic features of Nocardia keratitis in a patient who developed bilateral infection following photorefractive keratectomy (PRK). Case Report: A 23-year-old woman underwent bilateral PRK for low myopia. On postoperative day 3, dense central stromal infiltrates were noticed in both eyes. Empirical antibiotic therapy was initiated which was converted into specific therapy after a definite diagnosis was made based on clinical features and confirmed by confocal scan and histopathologic findings. Clinical and confocal scan features were consistent with the diagnosis of Nocardia keratitis, and topical 2% amikacin eye drops were started. Because of poor response to medical therapy, lamellar keratectomy was performed in both eyes which shortened the treatment course. Histopathologic examination reconfirmed the initial diagnosis. Conclusion: Familiarity with clinical and confocal scan features facilitates early diagnosis of Nocardia keratitis leading to proper management and hence a rapid therapeutic response.
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spelling doaj.art-c6248bf948b74e4d9494d021d7393c1d2022-12-22T03:27:09ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2012-01-0172162166Bilateral Nocardia Keratitis after Photorefractive KeratectomyAmir FaramarziSepehr FeiziMohammad-Ali JavadiMozhgan Rezaei KanaviForouzan YazdizadehHamid-Reza MoeinPurpose: To report the clinical, confocal scan, and histopathologic features of Nocardia keratitis in a patient who developed bilateral infection following photorefractive keratectomy (PRK). Case Report: A 23-year-old woman underwent bilateral PRK for low myopia. On postoperative day 3, dense central stromal infiltrates were noticed in both eyes. Empirical antibiotic therapy was initiated which was converted into specific therapy after a definite diagnosis was made based on clinical features and confirmed by confocal scan and histopathologic findings. Clinical and confocal scan features were consistent with the diagnosis of Nocardia keratitis, and topical 2% amikacin eye drops were started. Because of poor response to medical therapy, lamellar keratectomy was performed in both eyes which shortened the treatment course. Histopathologic examination reconfirmed the initial diagnosis. Conclusion: Familiarity with clinical and confocal scan features facilitates early diagnosis of Nocardia keratitis leading to proper management and hence a rapid therapeutic response.http://www.jovr.org/article.asp?issn=2008-322X;year=2012;volume=7;issue=2;spage=162;epage=166;aulast=FaramarziNocardia Keratitis; Photorefractive Keratectomy; Confocal Scan
spellingShingle Amir Faramarzi
Sepehr Feizi
Mohammad-Ali Javadi
Mozhgan Rezaei Kanavi
Forouzan Yazdizadeh
Hamid-Reza Moein
Bilateral Nocardia Keratitis after Photorefractive Keratectomy
Journal of Ophthalmic & Vision Research
Nocardia Keratitis; Photorefractive Keratectomy; Confocal Scan
title Bilateral Nocardia Keratitis after Photorefractive Keratectomy
title_full Bilateral Nocardia Keratitis after Photorefractive Keratectomy
title_fullStr Bilateral Nocardia Keratitis after Photorefractive Keratectomy
title_full_unstemmed Bilateral Nocardia Keratitis after Photorefractive Keratectomy
title_short Bilateral Nocardia Keratitis after Photorefractive Keratectomy
title_sort bilateral nocardia keratitis after photorefractive keratectomy
topic Nocardia Keratitis; Photorefractive Keratectomy; Confocal Scan
url http://www.jovr.org/article.asp?issn=2008-322X;year=2012;volume=7;issue=2;spage=162;epage=166;aulast=Faramarzi
work_keys_str_mv AT amirfaramarzi bilateralnocardiakeratitisafterphotorefractivekeratectomy
AT sepehrfeizi bilateralnocardiakeratitisafterphotorefractivekeratectomy
AT mohammadalijavadi bilateralnocardiakeratitisafterphotorefractivekeratectomy
AT mozhganrezaeikanavi bilateralnocardiakeratitisafterphotorefractivekeratectomy
AT forouzanyazdizadeh bilateralnocardiakeratitisafterphotorefractivekeratectomy
AT hamidrezamoein bilateralnocardiakeratitisafterphotorefractivekeratectomy