The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)

Abstract Background The number of older people living with HIV (PLWH) is increasing. Although there are many studies affecting medication adherence, research on the impact of social capital and mental health on medication adherence in this particular population is limited. Method Data were collected...

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Main Authors: Lei He, Bin Yu, Jun Yu, Jun Xiong, Yuling Huang, Tian Xie, Qi Chai, Bo Gao, Shujuan Yang
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Public Health
Subjects:
Online Access:https://doi.org/10.1186/s12889-021-12251-0
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author Lei He
Bin Yu
Jun Yu
Jun Xiong
Yuling Huang
Tian Xie
Qi Chai
Bo Gao
Shujuan Yang
author_facet Lei He
Bin Yu
Jun Yu
Jun Xiong
Yuling Huang
Tian Xie
Qi Chai
Bo Gao
Shujuan Yang
author_sort Lei He
collection DOAJ
description Abstract Background The number of older people living with HIV (PLWH) is increasing. Although there are many studies affecting medication adherence, research on the impact of social capital and mental health on medication adherence in this particular population is limited. Method Data were collected from an ongoing observational prospective cohort study, starting from November 2018, among older PLWH in Sichuan province, China. Five hundred twenty-one participants were interviewed. Social capital consists of the individual and family (IF) scale, and the community and society (CS) scale. The presence of probable depression and probable anxiety were assessed using the CES-D-10 and GAD-7 scales. Adherence was defined as taking ≥80% of prescribed HIV medication in 4 days prior to the interview. Two sets of Firth’ penalized regression analyses were used to estimate the association between social capital, mental health, and medication adherence. Results The prevalence of non-adherence was 18.2% (95/521) among older PLWH in this study. After adjusting for significant factors, the CS social capital (OR: 0.92, 95%CI:0.85–0.99, p < 0.05) and probable anxiety (OR:1.73, 95%CI:1.07–2.80, p < 0.05) were associated with non-adherence. Conclusion This study highlighted that the effects of social capital and mental health on older PLWH’s adherence, which implied that the need to develop interventions to concern for mental health and enhance CS social capital to help the older PLWH better manage HIV medication adherence.
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spelling doaj.art-c626828f564347e6b9a5dfb21c03378b2022-12-21T22:41:44ZengBMCBMC Public Health1471-24582021-12-012111810.1186/s12889-021-12251-0The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)Lei He0Bin Yu1Jun Yu2Jun Xiong3Yuling Huang4Tian Xie5Qi Chai6Bo Gao7Shujuan Yang8West China School of Public Health and West China Fourth Hospital, Sichuan UniversityWest China Second University Hospital of Sichuan University and Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of EducationLu County Center for Disease Control and PreventionLu County Center for Disease Control and PreventionSichuan Center for Disease Control and PreventionPidu District Center for Disease Control and PreventionWest China School of Public Health and West China Fourth Hospital, Sichuan UniversityWest China School of Public Health and West China Fourth Hospital, Sichuan UniversityWest China School of Public Health and West China Fourth Hospital, Sichuan UniversityAbstract Background The number of older people living with HIV (PLWH) is increasing. Although there are many studies affecting medication adherence, research on the impact of social capital and mental health on medication adherence in this particular population is limited. Method Data were collected from an ongoing observational prospective cohort study, starting from November 2018, among older PLWH in Sichuan province, China. Five hundred twenty-one participants were interviewed. Social capital consists of the individual and family (IF) scale, and the community and society (CS) scale. The presence of probable depression and probable anxiety were assessed using the CES-D-10 and GAD-7 scales. Adherence was defined as taking ≥80% of prescribed HIV medication in 4 days prior to the interview. Two sets of Firth’ penalized regression analyses were used to estimate the association between social capital, mental health, and medication adherence. Results The prevalence of non-adherence was 18.2% (95/521) among older PLWH in this study. After adjusting for significant factors, the CS social capital (OR: 0.92, 95%CI:0.85–0.99, p < 0.05) and probable anxiety (OR:1.73, 95%CI:1.07–2.80, p < 0.05) were associated with non-adherence. Conclusion This study highlighted that the effects of social capital and mental health on older PLWH’s adherence, which implied that the need to develop interventions to concern for mental health and enhance CS social capital to help the older PLWH better manage HIV medication adherence.https://doi.org/10.1186/s12889-021-12251-0HIVSocial capitalMental healthMedication adherence
spellingShingle Lei He
Bin Yu
Jun Yu
Jun Xiong
Yuling Huang
Tian Xie
Qi Chai
Bo Gao
Shujuan Yang
The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)
BMC Public Health
HIV
Social capital
Mental health
Medication adherence
title The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)
title_full The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)
title_fullStr The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)
title_full_unstemmed The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)
title_short The impact of social capital and mental health on medication adherence among older people living with HIV (PLWH)
title_sort impact of social capital and mental health on medication adherence among older people living with hiv plwh
topic HIV
Social capital
Mental health
Medication adherence
url https://doi.org/10.1186/s12889-021-12251-0
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