<i>O</i><sup>6</sup>-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability
The genome of living cells is continuously exposed to endogenous and exogenous attacks, and this is particularly amplified at high temperatures. Alkylating agents cause DNA damage, leading to mutations and cell death; for this reason, they also play a central role in chemotherapy treatments. A class...
Main Authors: | Rosanna Mattossovich, Rosa Merlo, Riccardo Miggiano, Anna Valenti, Giuseppe Perugino |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/8/2878 |
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