Occupational risks evaluation in a centralized antineoplastic agent preparation unit

Objective: The global professional risk assessment applied to the central unit of antineoplastic agent preparations is part of a mandatory approach required by the European legislation for workers. This study identified the hazardous situations related to the staff activity and then enabled the prep...

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Main Authors: Quentin Dubray, Taibou Diallo, Richard Loeuillet, Emilie Andre, Anne-Sophie Fauqueur, Sandrine Poil, Nathalie Thromas, Philippe-Henri Secretan, Salvatore Cisternino, Joël Schlatter
Format: Article
Language:English
Published: SAGE Publishing 2019-07-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/2050312119866970
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author Quentin Dubray
Taibou Diallo
Richard Loeuillet
Emilie Andre
Anne-Sophie Fauqueur
Sandrine Poil
Nathalie Thromas
Philippe-Henri Secretan
Salvatore Cisternino
Joël Schlatter
author_facet Quentin Dubray
Taibou Diallo
Richard Loeuillet
Emilie Andre
Anne-Sophie Fauqueur
Sandrine Poil
Nathalie Thromas
Philippe-Henri Secretan
Salvatore Cisternino
Joël Schlatter
author_sort Quentin Dubray
collection DOAJ
description Objective: The global professional risk assessment applied to the central unit of antineoplastic agent preparations is part of a mandatory approach required by the European legislation for workers. This study identified the hazardous situations related to the staff activity and then enabled the preparation of a formal plan of occupational prevention. Methods: The nature of study approved by a working group constituted by experts was the global risk analysis. After identifying the hazardous situations, the global risk analysis estimated the risk level of each hazardous situation based on a criticality score, including severity and frequency. The global risk analysis highlighted the initial and residual risks after establishing a plan to reduce the high criticality risks. Results: Hence, 33 unacceptable hazardous situations were identified. The critical categories of professional risks were “Product, emissions, and waste risks” with 17 (55%) hazardous situations; “Psychosocial risk factors” with 8 (24%) hazardous situations; and “Risks related to work equipment” with 6 (18%) hazardous situations. Once the risk reduction plan was in place, all hazardous situations were considered under control. The corrective actions led to a reorganization of human resources, the update of protection protocols, and optimization of ergonomic work tools. Staff-specific medical monitoring and regular surface contamination tests have been scheduled annually. In addition, initial and continuous training, specific to product and waste risks, has been updated. Conclusion: The global professional risk assessment related to centralized antineoplastic agent preparation unit generated failure in our system and enabled corrective actions for staff safety.
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spelling doaj.art-c62dd7e786034c12a646d368075a93e72022-12-22T04:11:44ZengSAGE PublishingSAGE Open Medicine2050-31212019-07-01710.1177/2050312119866970Occupational risks evaluation in a centralized antineoplastic agent preparation unitQuentin Dubray0Taibou Diallo1Richard Loeuillet2Emilie Andre3Anne-Sophie Fauqueur4Sandrine Poil5Nathalie Thromas6Philippe-Henri Secretan7Salvatore Cisternino8Joël Schlatter9Pharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FranceINSERM UMR-S 1144, Paris, FrancePharmacie, Hôpital Universitaire Necker – Enfants Malades, Paris, FranceObjective: The global professional risk assessment applied to the central unit of antineoplastic agent preparations is part of a mandatory approach required by the European legislation for workers. This study identified the hazardous situations related to the staff activity and then enabled the preparation of a formal plan of occupational prevention. Methods: The nature of study approved by a working group constituted by experts was the global risk analysis. After identifying the hazardous situations, the global risk analysis estimated the risk level of each hazardous situation based on a criticality score, including severity and frequency. The global risk analysis highlighted the initial and residual risks after establishing a plan to reduce the high criticality risks. Results: Hence, 33 unacceptable hazardous situations were identified. The critical categories of professional risks were “Product, emissions, and waste risks” with 17 (55%) hazardous situations; “Psychosocial risk factors” with 8 (24%) hazardous situations; and “Risks related to work equipment” with 6 (18%) hazardous situations. Once the risk reduction plan was in place, all hazardous situations were considered under control. The corrective actions led to a reorganization of human resources, the update of protection protocols, and optimization of ergonomic work tools. Staff-specific medical monitoring and regular surface contamination tests have been scheduled annually. In addition, initial and continuous training, specific to product and waste risks, has been updated. Conclusion: The global professional risk assessment related to centralized antineoplastic agent preparation unit generated failure in our system and enabled corrective actions for staff safety.https://doi.org/10.1177/2050312119866970
spellingShingle Quentin Dubray
Taibou Diallo
Richard Loeuillet
Emilie Andre
Anne-Sophie Fauqueur
Sandrine Poil
Nathalie Thromas
Philippe-Henri Secretan
Salvatore Cisternino
Joël Schlatter
Occupational risks evaluation in a centralized antineoplastic agent preparation unit
SAGE Open Medicine
title Occupational risks evaluation in a centralized antineoplastic agent preparation unit
title_full Occupational risks evaluation in a centralized antineoplastic agent preparation unit
title_fullStr Occupational risks evaluation in a centralized antineoplastic agent preparation unit
title_full_unstemmed Occupational risks evaluation in a centralized antineoplastic agent preparation unit
title_short Occupational risks evaluation in a centralized antineoplastic agent preparation unit
title_sort occupational risks evaluation in a centralized antineoplastic agent preparation unit
url https://doi.org/10.1177/2050312119866970
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