MicroRNA-223-3p downregulates the inflammatory response in preeclampsia placenta via targeting NLRP3

MicroRNA-223-3p downregulates the inflammatory response in preeclampsia placenta via targeting NLRP3

Abstract Objective To investigate the regulatory role of miR-223-3p in the inflammatory response of PE placenta. Methods PE and normal placental tissues were collected to measure the expression of NLRP3 and miR-223-3p. The targeting relationship between NLRP3 and miR-223-3P was verified by bioinform...

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Bibliographic Details
Main Authors: Xueqiong Liu, Zhiyue Li, Dan Lu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Pregnancy and Childbirth
Subjects:
Preeclampsia
Placenta inflammatory dysregulation
NLRP3 inflammasome
microRNA-223-3p
Online Access:https://doi.org/10.1186/s12884-024-06371-9

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