Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy
We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). Rapid anatomical and functional improvement was observed after a single intr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2012-06-01
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| Series: | Case Reports in Ophthalmology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/339656 |
| _version_ | 1828445269664989184 |
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| author | Maria G. Kotoula Fani Zacharaki Evangelia E. Tsironi |
| author_facet | Maria G. Kotoula Fani Zacharaki Evangelia E. Tsironi |
| author_sort | Maria G. Kotoula |
| collection | DOAJ |
| description | We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). Rapid anatomical and functional improvement was observed after a single intravitreal injection of bevacizumab. To our knowledge, we report the first case of PDT-treated CSC complicated by severe visual loss. We can only speculate that the serous detachment of the posterior pole might have been caused by PDT-induced VEGF overexpression, explaining such an impressive response to Avastin treatment. |
| first_indexed | 2024-12-10T21:55:52Z |
| format | Article |
| id | doaj.art-c62fdd88b92d485594dda8de3cf5794b |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-12-10T21:55:52Z |
| publishDate | 2012-06-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-c62fdd88b92d485594dda8de3cf5794b2022-12-22T01:32:03ZengKarger PublishersCase Reports in Ophthalmology1663-26992012-06-013219619910.1159/000339656339656Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous ChorioretinopathyMaria G. KotoulaFani ZacharakiEvangelia E. TsironiWe present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). Rapid anatomical and functional improvement was observed after a single intravitreal injection of bevacizumab. To our knowledge, we report the first case of PDT-treated CSC complicated by severe visual loss. We can only speculate that the serous detachment of the posterior pole might have been caused by PDT-induced VEGF overexpression, explaining such an impressive response to Avastin treatment.http://www.karger.com/Article/FullText/339656BevacizumabCentral serous chorioretinopathyPhotodynamic therapy |
| spellingShingle | Maria G. Kotoula Fani Zacharaki Evangelia E. Tsironi Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy Case Reports in Ophthalmology Bevacizumab Central serous chorioretinopathy Photodynamic therapy |
| title | Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy |
| title_full | Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy |
| title_fullStr | Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy |
| title_full_unstemmed | Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy |
| title_short | Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy |
| title_sort | intravitreal bevacizumab for photodynamic therapy induced massive macular detachment in acute central serous chorioretinopathy |
| topic | Bevacizumab Central serous chorioretinopathy Photodynamic therapy |
| url | http://www.karger.com/Article/FullText/339656 |
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