WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]

Multimodal monitoring of the brain generates a great quantity of data, providing the potential for great insight into both healthy and injured cerebral dynamics. In particular, near-infrared spectroscopy can be used to measure various physiological variables of interest, such as haemoglobin oxygenat...

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Main Authors: Joshua Russell-Buckland, Matthew Caldwell, Ilias Tachtsidis
Format: Article
Language:English
Published: Wellcome 2017-07-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/2-56/v1
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author Joshua Russell-Buckland
Matthew Caldwell
Ilias Tachtsidis
author_facet Joshua Russell-Buckland
Matthew Caldwell
Ilias Tachtsidis
author_sort Joshua Russell-Buckland
collection DOAJ
description Multimodal monitoring of the brain generates a great quantity of data, providing the potential for great insight into both healthy and injured cerebral dynamics. In particular, near-infrared spectroscopy can be used to measure various physiological variables of interest, such as haemoglobin oxygenation and the redox state of cytochrome-c-oxidase, alongside systemic signals, such as blood pressure. Interpreting these measurements is a complex endeavour, and much work has been done to develop mathematical models that can help to provide understanding of the underlying processes that contribute to the overall dynamics. BCMD is a software framework that was developed to run such models. However, obtaining, installing and running this software is no simple task. Here we present WeBCMD, an online environment that attempts to make the process simpler and much more accessible. By leveraging modern web technologies, an extensible and cross-platform package has been created that can also be accessed remotely from the cloud. WeBCMD is available as a Docker image and an online service.
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spelling doaj.art-c6325bc414be4ac1abd741e8ed31be482022-12-21T20:28:42ZengWellcomeWellcome Open Research2398-502X2017-07-01210.12688/wellcomeopenres.12201.113208WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]Joshua Russell-Buckland0Matthew Caldwell1Ilias Tachtsidis2Department of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UKDepartment of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UKDepartment of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UKMultimodal monitoring of the brain generates a great quantity of data, providing the potential for great insight into both healthy and injured cerebral dynamics. In particular, near-infrared spectroscopy can be used to measure various physiological variables of interest, such as haemoglobin oxygenation and the redox state of cytochrome-c-oxidase, alongside systemic signals, such as blood pressure. Interpreting these measurements is a complex endeavour, and much work has been done to develop mathematical models that can help to provide understanding of the underlying processes that contribute to the overall dynamics. BCMD is a software framework that was developed to run such models. However, obtaining, installing and running this software is no simple task. Here we present WeBCMD, an online environment that attempts to make the process simpler and much more accessible. By leveraging modern web technologies, an extensible and cross-platform package has been created that can also be accessed remotely from the cloud. WeBCMD is available as a Docker image and an online service.https://wellcomeopenresearch.org/articles/2-56/v1Bioinformatics
spellingShingle Joshua Russell-Buckland
Matthew Caldwell
Ilias Tachtsidis
WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]
Wellcome Open Research
Bioinformatics
title WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]
title_full WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]
title_fullStr WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]
title_full_unstemmed WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]
title_short WeBCMD: A cross-platform interface for the BCMD modelling framework [version 1; referees: 2 approved]
title_sort webcmd a cross platform interface for the bcmd modelling framework version 1 referees 2 approved
topic Bioinformatics
url https://wellcomeopenresearch.org/articles/2-56/v1
work_keys_str_mv AT joshuarussellbuckland webcmdacrossplatforminterfaceforthebcmdmodellingframeworkversion1referees2approved
AT matthewcaldwell webcmdacrossplatforminterfaceforthebcmdmodellingframeworkversion1referees2approved
AT iliastachtsidis webcmdacrossplatforminterfaceforthebcmdmodellingframeworkversion1referees2approved