Modulating protein quality control

Modulating protein quality control

Small molecules that modulate the unfolded protein response have the potential to treat a variety of human protein misfolding diseases.

Bibliographic Details
Main Authors: Lars Plate, Ryan J Paxman, R Luke Wiseman, Jeffery W Kelly
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
endoplasmic reticulum
unfolded protein response
small molecule screening
ATF6-alpha
ER stress
site-1-protease
Online Access:https://elifesciences.org/articles/18431
Description
Summary:Small molecules that modulate the unfolded protein response have the potential to treat a variety of human protein misfolding diseases.
ISSN:2050-084X

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