Genome editing in the unicellular holozoan Capsaspora owczarzaki suggests a premetazoan role for the Hippo pathway in multicellular morphogenesis

Genome editing in the unicellular holozoan Capsaspora owczarzaki suggests a premetazoan role for the Hippo pathway in multicellular morphogenesis

Animal development is mediated by a surprisingly small set of canonical signaling pathways such as Wnt, Hedgehog, TGF-beta, Notch, and Hippo pathways. Although once thought to be present only in animals, recent genome sequencing has revealed components of these pathways in the closest unicellular re...

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Bibliographic Details
Main Authors: Jonathan E Phillips, Maribel Santos, Mohammed Konchwala, Chao Xing, Duojia Pan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
Capsaspora owczarzaki
Hippo pathway
multicellularity
morphogenesis
cytoskeleton
cell proliferation
Online Access:https://elifesciences.org/articles/77598

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