An unusual case of shortness of breath
Myopathy is a well-known complication of hypercortisolism and commonly involves proximal lower-limb girdle. We report a rare case of Cushing’s syndrome in a 60-year-old female presenting with significant respiratory muscle weakness and respiratory failure. She had history of rheumatoid arthritis, pr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Bioscientifica
2018-07-01
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| Series: | Endocrinology, Diabetes & Metabolism Case Reports |
| Online Access: | https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-18-0074 |
| _version_ | 1818422697915318272 |
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| author | S F Wan Muhammad Hatta L Kandaswamy C Gherman-Ciolac J Mann H N Buch |
| author_facet | S F Wan Muhammad Hatta L Kandaswamy C Gherman-Ciolac J Mann H N Buch |
| author_sort | S F Wan Muhammad Hatta |
| collection | DOAJ |
| description | Myopathy is a well-known complication of hypercortisolism and commonly involves proximal lower-limb girdle. We report a rare case of Cushing’s syndrome in a 60-year-old female presenting with significant respiratory muscle weakness and respiratory failure. She had history of rheumatoid arthritis, primary biliary cirrhosis and primary hypothyroidism and presented with weight gain and increasing shortness of breath. Investigations confirmed a restrictive defect with impaired gas transfer but with no significant parenchymatous pulmonary disease. Respiratory muscle test confirmed weakness of respiratory muscles and diaphragm. Biochemical and radiological investigations confirmed hypercortisolaemia secondary to a left adrenal tumour. Following adrenalectomy her respiratory symptoms improved along with an objective improvement in the respiratory muscle strength, diaphragmatic movement and pulmonary function test. |
| first_indexed | 2024-12-14T13:30:23Z |
| format | Article |
| id | doaj.art-c640725f75644fb083168df1d3c59df8 |
| institution | Directory Open Access Journal |
| issn | 2052-0573 2052-0573 |
| language | English |
| last_indexed | 2024-12-14T13:30:23Z |
| publishDate | 2018-07-01 |
| publisher | Bioscientifica |
| record_format | Article |
| series | Endocrinology, Diabetes & Metabolism Case Reports |
| spelling | doaj.art-c640725f75644fb083168df1d3c59df82022-12-21T22:59:44ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732052-05732018-07-01111510.1530/EDM-18-0074An unusual case of shortness of breathS F Wan Muhammad Hatta0L Kandaswamy1C Gherman-Ciolac2J Mann3H N Buch4New Cross Hospital, Wolverhampton, UK; Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, 47000 Sungai Buloh, Selangor, MalaysiaNew Cross Hospital, Wolverhampton, UKNew Cross Hospital, Wolverhampton, UKNew Cross Hospital, Wolverhampton, UKNew Cross Hospital, Wolverhampton, UKMyopathy is a well-known complication of hypercortisolism and commonly involves proximal lower-limb girdle. We report a rare case of Cushing’s syndrome in a 60-year-old female presenting with significant respiratory muscle weakness and respiratory failure. She had history of rheumatoid arthritis, primary biliary cirrhosis and primary hypothyroidism and presented with weight gain and increasing shortness of breath. Investigations confirmed a restrictive defect with impaired gas transfer but with no significant parenchymatous pulmonary disease. Respiratory muscle test confirmed weakness of respiratory muscles and diaphragm. Biochemical and radiological investigations confirmed hypercortisolaemia secondary to a left adrenal tumour. Following adrenalectomy her respiratory symptoms improved along with an objective improvement in the respiratory muscle strength, diaphragmatic movement and pulmonary function test.https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-18-0074 |
| spellingShingle | S F Wan Muhammad Hatta L Kandaswamy C Gherman-Ciolac J Mann H N Buch An unusual case of shortness of breath Endocrinology, Diabetes & Metabolism Case Reports |
| title | An unusual case of shortness of breath |
| title_full | An unusual case of shortness of breath |
| title_fullStr | An unusual case of shortness of breath |
| title_full_unstemmed | An unusual case of shortness of breath |
| title_short | An unusual case of shortness of breath |
| title_sort | unusual case of shortness of breath |
| url | https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-18-0074 |
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