Characteristics of measles immunity in students of the pediatric faculty of a medical university

Objective: to evaluate the intensity of measles immunity in students of I–VI courses of the pediatric faculty of St. Petersburg State Medical University.Materials and methods: titers of antibodies to measles virus were determined in 986 students of I–VI courses in May –June 2019. The level of measle...

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Bibliographic Details
Main Authors: D. O. Ivanov, V. N. Timchenko, E. B. Pavlova, E. V. Barakina, T. M. Chernova, N. V. Pavlova, O. V. Bulina, A. N. Nazarova
Format: Article
Language:Russian
Published: Journal Infectology 2020-10-01
Series:Журнал инфектологии
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Online Access:https://journal.niidi.ru/jofin/article/view/1103
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Summary:Objective: to evaluate the intensity of measles immunity in students of I–VI courses of the pediatric faculty of St. Petersburg State Medical University.Materials and methods: titers of antibodies to measles virus were determined in 986 students of I–VI courses in May –June 2019. The level of measles antibodies was determined by enzyme-linked immunosorbent assay.Results: positive (protective) titres of measles antibodies were detected in 555 people. (56.4%), the absence of measles immunity was found in 431 people. (43.6%), including 57 people. (5.8%) specific antibodies were not detected. The relationship between the level of collective immunity and the duration of the period after the last vaccination against measles was revealed.Conclusions: in the majority of examined students (96.2%), protective titers of measles antibodies remained for 10 years after the last vaccination. Subsequently, a significant decrease in the level of measles antibodies was noted. All students who do not have a protective IgG titer are shown measles vaccination with live measles vaccine in accordance with the instructions for use.
ISSN:2072-6732