Modulation of natural killer cell functions by interactions between 2B4 and CD48 in cis and in trans

SLAM-related receptors (SRRs) are important modulators of immune cell function. While most SRRs are homophilic, 2B4 (CD244) interacts with CD48, a GPI-anchored protein expressed on many haematopoietic cells. Here we show that natural killer (NK) cell-expressed 2B4 not only binds in trans to CD48 on...

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Bibliografiska uppgifter
Huvudupphovsmän: Maren Claus, Sabine Wingert, Carsten Watzl
Materialtyp: Artikel
Språk:English
Publicerad: The Royal Society 2016-01-01
Serie:Open Biology
Ämnen:
Länkar:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160010