PragmaTic, prospEctive, randomized, controlled, double-blind, mulTi-centre, multinational study on the safety and efficacy of a 6% HydroxYethyl Starch (HES) solution versus an electrolyte solution in trauma patients: study protocol for the TETHYS study

PragmaTic, prospEctive, randomized, controlled, double-blind, mulTi-centre, multinational study on the safety and efficacy of a 6% HydroxYethyl Starch (HES) solution versus an electrolyte solution in trauma patients: study protocol for the TETHYS study

Abstract Background Trauma may be associated with significant to life-threatening blood loss, which in turn may increase the risk of complications and death, particularly in the absence of adequate treatment. Hydroxyethyl starch (HES) solutions are used for volume therapy to treat hypovolemia due to...

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Bibliographic Details
Main Authors: Clementina Duran Palma, Musawenkosi Mamba, Johan Geldenhuys, Oluwafolajimi Fadahun, Rolf Rossaint, Kai Zacharowski, Martin Brand, Óscar Díaz-Cambronero, Javier Belda, Martin Westphal, Ute Brauer, Dirk Dormann, Tamara Dehnhardt, Martin Hernandez-Gonzalez, Sonja Schmier, Dianne de Korte, Frank Plani, Wolfgang Buhre
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Trials
Subjects:
Volume therapy
Colloids
Hydroxyethyl starch
HES
Trauma
Blood loss
Online Access:https://doi.org/10.1186/s13063-022-06390-x

Internet

https://doi.org/10.1186/s13063-022-06390-x

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