Kahweol Induces Apoptosis in Hepatocellular Carcinoma Cells by Inhibiting the Src/mTOR/STAT3 Signaling Pathway

Kahweol Induces Apoptosis in Hepatocellular Carcinoma Cells by Inhibiting the Src/mTOR/STAT3 Signaling Pathway

Kahweol, a coffee-specific diterpene, induces apoptosis in human cancer cells, and some targets of kahweol-mediated apoptosis have been identified. However, the specific apoptotic effects and mechanism of action of kahweol in hepatocellular carcinoma (HCC) cells are unknown. This study was performed...

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Bibliographic Details
Main Authors: Hye-Young Seo, So-Hee Lee, Ji-Ha Lee, Jae-Ho Lee, Byoung Kuk Jang, Mi Kyung Kim
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
kahweol
Src kinase
HCC
apoptosis
Online Access:https://www.mdpi.com/1422-0067/22/19/10509

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