Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary Disease
Maximal voluntary inspiratory breath-holding time (MVIBHT) has proved to be of clinical utility in some obstructive ventilatory defects. This study aims to correlate the breath-holding time with pulmonary function tests in patients with chronic obstructive pulmonary disease (COPD) and to determine t...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-05-01
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| Series: | American Journal of Men's Health |
| Online Access: | https://doi.org/10.1177/15579883211015857 |
| _version_ | 1818945177355550720 |
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| author | Abir Hedhli Azza Slim Yassine Ouahchi Meriem Mjid Jamel Koumenji Sana Cheikh Rouhou Sonia Toujani Besma Dhahri |
| author_facet | Abir Hedhli Azza Slim Yassine Ouahchi Meriem Mjid Jamel Koumenji Sana Cheikh Rouhou Sonia Toujani Besma Dhahri |
| author_sort | Abir Hedhli |
| collection | DOAJ |
| description | Maximal voluntary inspiratory breath-holding time (MVIBHT) has proved to be of clinical utility in some obstructive ventilatory defects. This study aims to correlate the breath-holding time with pulmonary function tests in patients with chronic obstructive pulmonary disease (COPD) and to determine the feasibility of using a breath-holding test in assessing the severity of COPD. A cross-sectional study including male patients with stable COPD were conducted. Patients with respiratory comorbidities and severe or unstable cardiac diseases were excluded. Patients were interviewed and examined. Six-minute walk test (6MWT) and plethysmography were performed.For MVIBHT collection, the subject was asked to inspire deeply and to hold the breath as long as possible at the maximum inspiratory level. This maneuver was repeated three times. The best value was used for further analysis. A total of 79 patients (mean age: 64.2 ± 8) were included in this study. The mean value of MVIBHT was 24.2 ± 8.5 s. We identified a positive and significant correlations between MVIBHT and forced vital capacity ( r = .630; p < .001) as well as MVIBHT and forced expiratory volume in 1 s (FEV1%) ( r = .671; p < .001). A significant inverse correlation with total lung capacity ( r = −.328; p = .019) and residual volume to total lung capacity ratio ( r = −.607; p < .001) was noted. MVIBHT was significantly correlated to the distance in the 6MWT ( r = .494; p < .001). The mean MVIBHT was significantly different within spirometric grades ( p < .001) and GOLD groups ( p = .002). At 20.5 s, MVIBHT had a sensitivity of 72% and specificity of 96% in determining COPD patients with FEV1 <50%. Our results provide additional evidence of the usefulness of MVIBHT in COPD patients as a pulmonary function parameter. |
| first_indexed | 2024-12-20T07:54:58Z |
| format | Article |
| id | doaj.art-c65ba42a2e074b8490cf6314fabc5a94 |
| institution | Directory Open Access Journal |
| issn | 1557-9891 |
| language | English |
| last_indexed | 2024-12-20T07:54:58Z |
| publishDate | 2021-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | American Journal of Men's Health |
| spelling | doaj.art-c65ba42a2e074b8490cf6314fabc5a942022-12-21T19:47:44ZengSAGE PublishingAmerican Journal of Men's Health1557-98912021-05-011510.1177/15579883211015857Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary DiseaseAbir Hedhli0Azza Slim1Yassine Ouahchi2Meriem Mjid3Jamel Koumenji4Sana Cheikh Rouhou5Sonia Toujani6Besma Dhahri7Pneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaPneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaPneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaPneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaPneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaPneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaPneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaPneumology Department, Research Laboratory RL18SP02, University of Tunis El Manar, La Rabta Hospital, Tunis, TunisiaMaximal voluntary inspiratory breath-holding time (MVIBHT) has proved to be of clinical utility in some obstructive ventilatory defects. This study aims to correlate the breath-holding time with pulmonary function tests in patients with chronic obstructive pulmonary disease (COPD) and to determine the feasibility of using a breath-holding test in assessing the severity of COPD. A cross-sectional study including male patients with stable COPD were conducted. Patients with respiratory comorbidities and severe or unstable cardiac diseases were excluded. Patients were interviewed and examined. Six-minute walk test (6MWT) and plethysmography were performed.For MVIBHT collection, the subject was asked to inspire deeply and to hold the breath as long as possible at the maximum inspiratory level. This maneuver was repeated three times. The best value was used for further analysis. A total of 79 patients (mean age: 64.2 ± 8) were included in this study. The mean value of MVIBHT was 24.2 ± 8.5 s. We identified a positive and significant correlations between MVIBHT and forced vital capacity ( r = .630; p < .001) as well as MVIBHT and forced expiratory volume in 1 s (FEV1%) ( r = .671; p < .001). A significant inverse correlation with total lung capacity ( r = −.328; p = .019) and residual volume to total lung capacity ratio ( r = −.607; p < .001) was noted. MVIBHT was significantly correlated to the distance in the 6MWT ( r = .494; p < .001). The mean MVIBHT was significantly different within spirometric grades ( p < .001) and GOLD groups ( p = .002). At 20.5 s, MVIBHT had a sensitivity of 72% and specificity of 96% in determining COPD patients with FEV1 <50%. Our results provide additional evidence of the usefulness of MVIBHT in COPD patients as a pulmonary function parameter.https://doi.org/10.1177/15579883211015857 |
| spellingShingle | Abir Hedhli Azza Slim Yassine Ouahchi Meriem Mjid Jamel Koumenji Sana Cheikh Rouhou Sonia Toujani Besma Dhahri Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary Disease American Journal of Men's Health |
| title | Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary Disease |
| title_full | Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary Disease |
| title_fullStr | Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary Disease |
| title_full_unstemmed | Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary Disease |
| title_short | Maximal Voluntary Breath-Holding Tele-Inspiratory Test in Patients with Chronic Obstructive Pulmonary Disease |
| title_sort | maximal voluntary breath holding tele inspiratory test in patients with chronic obstructive pulmonary disease |
| url | https://doi.org/10.1177/15579883211015857 |
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