Microarray Analysis of Differentially-Expressed Genes Encoding CYP450 and Phase II Drug Metabolizing Enzymes in Psoriasis and Melanoma

Microarray Analysis of Differentially-Expressed Genes Encoding CYP450 and Phase II Drug Metabolizing Enzymes in Psoriasis and Melanoma

Cytochrome P450 drug metabolizing enzymes are implicated in personalized medicine for two main reasons. First, inter-individual variability in CYP3A4 expression is a confounding factor during cancer treatment. Second, inhibition or induction of CYP3A4 can trigger adverse drug–drug interactions. Howe...

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Bibliographic Details
Main Authors: Venil N. Sumantran, Pratik Mishra, Rakesh Bera, Natarajan Sudhakar
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Pharmaceutics
Subjects:
psoriasis
melanoma
microarray
CYP450
drug metabolism
personalized medicine
Online Access:http://www.mdpi.com/1999-4923/8/1/4

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