Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate

Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate

Bisphosphonate drugs constitute the primary treatment for bone diseases such as Paget’s disease and osteoporosis. Despite their effectiveness, they also exhibit severe drawbacks, such as rapid excretion and limited oral bioavailability. High doses are usually administered to counterbalance these dra...

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Bibliographic Details
Main Authors: Fanouria-Eirini G. Alatzoglou, Maria Vassaki, Kalliopi Nirgianaki, Eleftherios Tripodianos, Petri Turhanen, Konstantinos D. Demadis, Konstantinos E. Papathanasiou
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Materials
Subjects:
silica gels
hydrogels
drug release
bisphosphonates
osteoporosis
controlled release
Online Access:https://www.mdpi.com/1996-1944/16/9/3379

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