DNA Methylation of Patatin-Like Phospholipase Domain-Containing Protein 6 Gene Contributes to the Risk of Intracranial Aneurysm in Males

DNA Methylation of Patatin-Like Phospholipase Domain-Containing Protein 6 Gene Contributes to the Risk of Intracranial Aneurysm in Males

Objective: This study is aimed to investigate the contribution of patatin-like phospholipase domain-containing protein 6 (PNPLA6) DNA methylation to the risk of intracranial aneurysm (IA) in the Han Chinese population.Methods: A total of 96 age- and sex-matched participants were recruited to evaluat...

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Bibliographic Details
Main Authors: Shengjun Zhou, Junjun Zhang, Chenhui Zhou, Fanyong Gong, Xueli Zhu, Xingqiang Pan, Jie Sun, Xiang Gao, Yi Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
PNPLA6
DNA methylation
mRNA expression
age
intracranial aneurysms
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.885680/full

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