Combined Assessment of the Tumor–Stroma Ratio and Tumor Immune Cell Infiltrate for Immune Checkpoint Inhibitor Therapy Response Prediction in Colon Cancer

Combined Assessment of the Tumor–Stroma Ratio and Tumor Immune Cell Infiltrate for Immune Checkpoint Inhibitor Therapy Response Prediction in Colon Cancer

The best current biomarker strategies for predicting response to immune checkpoint inhibitor (ICI) therapy fail to account for interpatient variability in response rates. The histologic tumor–stroma ratio (TSR) quantifies intratumoral stromal content and was recently found to be predictive of respon...

Full description

Bibliographic Details
Main Authors: Cor J. Ravensbergen, Meaghan Polack, Jessica Roelands, Stijn Crobach, Hein Putter, Hans Gelderblom, Rob A. E. M. Tollenaar, Wilma E. Mesker
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
tumor–stroma ratio
colon cancer
tumor-infiltrating immune cells
immunotherapy
tumor microenvironment
checkpoint inhibitor
Online Access:https://www.mdpi.com/2073-4409/10/11/2935

Similar Items

Similar Items