A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast
Dismounted complex blast injury (DCBI) has been one of the most severe forms of trauma sustained in recent conflicts. This injury has been partially attributed to limb flail; however, the full causative mechanism has not yet been fully determined. Soil ejecta has been hypothesized as a significant c...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-08-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00960/full |
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| author | Iain A. Rankin Thuy-Tien Nguyen Diagarajen Carpanen Jonathan C. Clasper Jonathan C. Clasper Spyros D. Masouros |
| author_facet | Iain A. Rankin Thuy-Tien Nguyen Diagarajen Carpanen Jonathan C. Clasper Jonathan C. Clasper Spyros D. Masouros |
| author_sort | Iain A. Rankin |
| collection | DOAJ |
| description | Dismounted complex blast injury (DCBI) has been one of the most severe forms of trauma sustained in recent conflicts. This injury has been partially attributed to limb flail; however, the full causative mechanism has not yet been fully determined. Soil ejecta has been hypothesized as a significant contributor to the injury but remains untested. In this study, a small-animal model of gas-gun mediated high velocity sand blast was used to investigate this mechanism. The results demonstrated a correlation between increasing sand blast velocity and injury patterns of worsening severity across the trauma range. This study is the first to replicate high velocity sand blast and the first model to reproduce the pattern of injury seen in DCBI. These findings are consistent with clinical and battlefield data. They represent a significant change in the understanding of blast injury, producing a new mechanistic theory of traumatic amputation. This mechanism of traumatic amputation is shown to be high velocity sand blast causing the initial tissue disruption, with the following blast wind and resultant limb flail completing the amputation. These findings implicate high velocity sand blast, in addition to limb flail, as a critical mechanism of injury in the dismounted blast casualty. |
| first_indexed | 2024-12-22T12:23:24Z |
| format | Article |
| id | doaj.art-c667dd25e682440c9ece13bcd135bb1e |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-22T12:23:24Z |
| publishDate | 2020-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-c667dd25e682440c9ece13bcd135bb1e2022-12-21T18:25:54ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852020-08-01810.3389/fbioe.2020.00960559957A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in BlastIain A. Rankin0Thuy-Tien Nguyen1Diagarajen Carpanen2Jonathan C. Clasper3Jonathan C. Clasper4Spyros D. Masouros5Department of Bioengineering, Imperial College London, London, United KingdomDepartment of Bioengineering, Imperial College London, London, United KingdomDepartment of Bioengineering, Imperial College London, London, United KingdomDepartment of Bioengineering, Imperial College London, London, United KingdomDepartment of Trauma and Orthopaedic Surgery, Frimley Park Hospital, Frimley, United KingdomDepartment of Bioengineering, Imperial College London, London, United KingdomDismounted complex blast injury (DCBI) has been one of the most severe forms of trauma sustained in recent conflicts. This injury has been partially attributed to limb flail; however, the full causative mechanism has not yet been fully determined. Soil ejecta has been hypothesized as a significant contributor to the injury but remains untested. In this study, a small-animal model of gas-gun mediated high velocity sand blast was used to investigate this mechanism. The results demonstrated a correlation between increasing sand blast velocity and injury patterns of worsening severity across the trauma range. This study is the first to replicate high velocity sand blast and the first model to reproduce the pattern of injury seen in DCBI. These findings are consistent with clinical and battlefield data. They represent a significant change in the understanding of blast injury, producing a new mechanistic theory of traumatic amputation. This mechanism of traumatic amputation is shown to be high velocity sand blast causing the initial tissue disruption, with the following blast wind and resultant limb flail completing the amputation. These findings implicate high velocity sand blast, in addition to limb flail, as a critical mechanism of injury in the dismounted blast casualty.https://www.frontiersin.org/article/10.3389/fbioe.2020.00960/fullbiomechanicstraumatic amputationfractureblast injurymilitarymouse |
| spellingShingle | Iain A. Rankin Thuy-Tien Nguyen Diagarajen Carpanen Jonathan C. Clasper Jonathan C. Clasper Spyros D. Masouros A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast Frontiers in Bioengineering and Biotechnology biomechanics traumatic amputation fracture blast injury military mouse |
| title | A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast |
| title_full | A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast |
| title_fullStr | A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast |
| title_full_unstemmed | A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast |
| title_short | A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast |
| title_sort | new understanding of the mechanism of injury to the pelvis and lower limbs in blast |
| topic | biomechanics traumatic amputation fracture blast injury military mouse |
| url | https://www.frontiersin.org/article/10.3389/fbioe.2020.00960/full |
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