Neural Circuits for Social Interactions: From Microcircuits to Input-Output Circuits
Social behaviors entail responses to social information and requires the perception and integration of social cues through a complex cognition process that involves attention, memory, motivation, and emotion. Neurobiological and molecular mechanisms underlying social behavior are highly conserved ac...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-10-01
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| Series: | Frontiers in Neural Circuits |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fncir.2021.768294/full |
| _version_ | 1818826547868467200 |
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| author | Sen Xu Ming Jiang Xia Liu Yahan Sun Liang Yang Qinghu Yang Zhantao Bai |
| author_facet | Sen Xu Ming Jiang Xia Liu Yahan Sun Liang Yang Qinghu Yang Zhantao Bai |
| author_sort | Sen Xu |
| collection | DOAJ |
| description | Social behaviors entail responses to social information and requires the perception and integration of social cues through a complex cognition process that involves attention, memory, motivation, and emotion. Neurobiological and molecular mechanisms underlying social behavior are highly conserved across species, and inter- and intra-specific variability observed in social behavior can be explained to large extent by differential activity of a conserved neural network. However, neural microcircuits and precise networks involved in social behavior remain mysterious. In this review, we summarize the microcircuits and input-output circuits on the molecular, cellular, and network levels of different social interactions, such as social exploration, social hierarchy, social memory, and social preference. This review provides a broad view of how multiple microcircuits and input-output circuits converge on the medial prefrontal cortex, hippocampus, and amygdala to regulate complex social behaviors, as well as a potential novel view for better control over pathological development. |
| first_indexed | 2024-12-19T00:29:24Z |
| format | Article |
| id | doaj.art-c66aeaf1ce564c78a2e039fe68b45a45 |
| institution | Directory Open Access Journal |
| issn | 1662-5110 |
| language | English |
| last_indexed | 2024-12-19T00:29:24Z |
| publishDate | 2021-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neural Circuits |
| spelling | doaj.art-c66aeaf1ce564c78a2e039fe68b45a452022-12-21T20:45:10ZengFrontiers Media S.A.Frontiers in Neural Circuits1662-51102021-10-011510.3389/fncir.2021.768294768294Neural Circuits for Social Interactions: From Microcircuits to Input-Output CircuitsSen XuMing JiangXia LiuYahan SunLiang YangQinghu YangZhantao BaiSocial behaviors entail responses to social information and requires the perception and integration of social cues through a complex cognition process that involves attention, memory, motivation, and emotion. Neurobiological and molecular mechanisms underlying social behavior are highly conserved across species, and inter- and intra-specific variability observed in social behavior can be explained to large extent by differential activity of a conserved neural network. However, neural microcircuits and precise networks involved in social behavior remain mysterious. In this review, we summarize the microcircuits and input-output circuits on the molecular, cellular, and network levels of different social interactions, such as social exploration, social hierarchy, social memory, and social preference. This review provides a broad view of how multiple microcircuits and input-output circuits converge on the medial prefrontal cortex, hippocampus, and amygdala to regulate complex social behaviors, as well as a potential novel view for better control over pathological development.https://www.frontiersin.org/articles/10.3389/fncir.2021.768294/fullsocial interactionmicrocircuitinput-output circuitmedial prefrontal cortexhippocampusamygdala |
| spellingShingle | Sen Xu Ming Jiang Xia Liu Yahan Sun Liang Yang Qinghu Yang Zhantao Bai Neural Circuits for Social Interactions: From Microcircuits to Input-Output Circuits Frontiers in Neural Circuits social interaction microcircuit input-output circuit medial prefrontal cortex hippocampus amygdala |
| title | Neural Circuits for Social Interactions: From Microcircuits to Input-Output Circuits |
| title_full | Neural Circuits for Social Interactions: From Microcircuits to Input-Output Circuits |
| title_fullStr | Neural Circuits for Social Interactions: From Microcircuits to Input-Output Circuits |
| title_full_unstemmed | Neural Circuits for Social Interactions: From Microcircuits to Input-Output Circuits |
| title_short | Neural Circuits for Social Interactions: From Microcircuits to Input-Output Circuits |
| title_sort | neural circuits for social interactions from microcircuits to input output circuits |
| topic | social interaction microcircuit input-output circuit medial prefrontal cortex hippocampus amygdala |
| url | https://www.frontiersin.org/articles/10.3389/fncir.2021.768294/full |
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