The Emerging Roles of Protein Interactions with O-GlcNAc Cycling Enzymes in Cancer

The Emerging Roles of Protein Interactions with O-GlcNAc Cycling Enzymes in Cancer

The dynamic O-GlcNAc modification of intracellular proteins is an important nutrient sensor for integrating metabolic signals into vast networks of highly coordinated cellular activities. Dysregulation of the sole enzymes responsible for O-GlcNAc cycling, O-GlcNAc transferase (OGT) and O-GlcNAcase (...

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Bibliographic Details
Main Authors: Chia-Wei Hu, Jinshan Xie, Jiaoyang Jiang
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
O-GlcNAcylation
O-GlcNAc transferase (OGT)
O-GlcNAcase (OGA)
cancer
protein–protein interaction (PPI)
Online Access:https://www.mdpi.com/2072-6694/14/20/5135

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