Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective
Silencing of STK25, an STE20-type kinase, in human aortic endothelial and smooth muscle cells reduces lipid accumulation and suppresses inflammation and fibrotic pathways, ultimately exerting atheroprotective effects.
Bibliographic Details
| Main Authors: |
Emmelie Cansby,
Sima Kumari,
Mara Caputo,
Ying Xia,
Rando Porosk,
Jonathan Robinson,
Hao Wang,
Britt-Marie Olsson,
Josefine Vallin,
Julie Grantham,
Ursel Soomets,
L. Thomas Svensson,
Carina Sihlbom,
Hanns-Ulrich Marschall,
Andreas Edsfeldt,
Isabel Goncalves,
Margit Mahlapuu |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-04-01
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| Series: | Communications Biology
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| Online Access: | https://doi.org/10.1038/s42003-022-03309-9
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