Microporous PdCuB nanotag-based electrochemical aptasensor with Au@CuCl2 nanowires interface for ultrasensitive detection of PD-L1-positive exosomes in the serum of lung cancer patients

Microporous PdCuB nanotag-based electrochemical aptasensor with Au@CuCl2 nanowires interface for ultrasensitive detection of PD-L1-positive exosomes in the serum of lung cancer patients

Abstract Programmed cell death ligand 1 protein-positive (PD-L1+) exosomes have been found to be a potential biomarker for the diagnosis of non-small cell lung cancer (NSCLC). However, the development of highly sensitive detection technique for PD-L1+ exosomes is still a challenge in clinical applic...

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Bibliographic Details
Main Authors: Luyue Chang, Haiping Wu, Rui Chen, Xiaoqing Sun, Yi Yang, Changwu Huang, Shijia Ding, Changjin Liu, Wei Cheng
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Nanobiotechnology
Subjects:
PD-L1+ exosome
Electrochemical aptasensor
Microporous PdCuB nanotag
Au@CuCl2 nanowires
Non-small cell lung cancer
Online Access:https://doi.org/10.1186/s12951-023-01845-y

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