Versatile and efficient genome editing with Neisseria cinerea Cas9
A Neisseria cinerea Cas9 variant is characterised in PAM preference, editing efficiency (for both nuclease and base editing) and anti-CRISPR protein blocking, with a PAM of (N)4GYAT reported alongside a mouse zygote assay.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04258-z |
| Summary: | A Neisseria cinerea Cas9 variant is characterised in PAM preference, editing efficiency (for both nuclease and base editing) and anti-CRISPR protein blocking, with a PAM of (N)4GYAT reported alongside a mouse zygote assay. |
|---|---|
| ISSN: | 2399-3642 |