The role of complement C3 in the outcome of regional myocardial infarction

Coronary heart disease leading to myocardial ischemia is a major cause of heart failure. A hallmark of heart failure is myocardial fibrosis. Using a murine model of myocardial ischemia/reperfusion injury (IRI), we showed that, following IRI, in mice genetically deficient in the central factor of com...

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Bibliographic Details
Main Authors: Zhou Fang, Xiang Li, Junying Liu, Haekyung Lee, Louis Salciccioli, Jason Lazar, Ming Zhang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000158