Therapeutic Uses of Bacterial Subunit Toxins
The B subunit pentamer verotoxin (VT aka Shiga toxin-Stx) binding to its cellular glycosphingolipid (GSL) receptor, globotriaosyl ceramide (Gb<sub>3</sub>) mediates internalization and the subsequent receptor mediated retrograde intracellular traffic of the AB5 subunit holotoxin to the e...
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Format: | Article |
Language: | English |
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MDPI AG
2021-05-01
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Series: | Toxins |
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Online Access: | https://www.mdpi.com/2072-6651/13/6/378 |