Therapeutic Uses of Bacterial Subunit Toxins

Therapeutic Uses of Bacterial Subunit Toxins

The B subunit pentamer verotoxin (VT aka Shiga toxin-Stx) binding to its cellular glycosphingolipid (GSL) receptor, globotriaosyl ceramide (Gb<sub>3</sub>) mediates internalization and the subsequent receptor mediated retrograde intracellular traffic of the AB5 subunit holotoxin to the e...

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Bibliographic Details
Main Author:	Clifford Lingwood
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	Toxins
Subjects:	retrograde transport neoplastic Gb<sub>3</sub> expression endoplasmic reticulum associated degradation protein misfolding diseases
Online Access:	https://www.mdpi.com/2072-6651/13/6/378

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