Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study
Objective To identify potential risk factors for cerebrospinal fluid (CSF) leakage after craniovertebral junction (CVJ) anomaly surgery and to provide a reference for clinical practice. Methods Sixty-six patients who underwent elective CVJ anomaly surgery during a 6-year period (April 2013 to Septem...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Spinal Neurosurgery Society
2023-03-01
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| Series: | Neurospine |
| Subjects: | |
| Online Access: | http://e-neurospine.org/upload/pdf/ns-2244772-386.pdf |
| _version_ | 1827360718347829248 |
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| author | Yu Xiao Bing Wang Yulian Chen Lingqiang Chen Zhenkai Lou Zhiqiang Gong |
| author_facet | Yu Xiao Bing Wang Yulian Chen Lingqiang Chen Zhenkai Lou Zhiqiang Gong |
| author_sort | Yu Xiao |
| collection | DOAJ |
| description | Objective To identify potential risk factors for cerebrospinal fluid (CSF) leakage after craniovertebral junction (CVJ) anomaly surgery and to provide a reference for clinical practice. Methods Sixty-six patients who underwent elective CVJ anomaly surgery during a 6-year period (April 2013 to September 2019) were retrospectively included. Research data were collected from the patients’ medical records and imaging systems. Patients were divided into CSF leak and no CSF leak groups. Univariate tests were performed to identify potential risk factors. For statistically significant variables in the univariate tests, a logistic regression test was used to identify independent risk factors for CSF leakage. Results The overall prevalence of CSF leakage was 13.64%. Univariate tests showed that a basion-dental interval (BDI) > 10 mm and occipitalized atlas had significant intergroup differences (p < 0.05). Multivariate analysis indicated that a BDI > 10 mm was an independent risk factor for CSF leakage, and patients with CVJ anomalies with a BDI > 10 mm were more likely to have postoperative CSF leaks (odds ratio, 14.67; 95% confidence interval, 1.48–30.88; p = 0.004). Conclusion It is necessary to maintain vigilance during CVJ anomaly surgery in patients with a preoperative BDI > 10 mm to avoid postoperative CSF leaks. |
| first_indexed | 2024-03-08T06:52:22Z |
| format | Article |
| id | doaj.art-c67aaf4e8bb2471696e865b6fbc51c3c |
| institution | Directory Open Access Journal |
| issn | 2586-6583 2586-6591 |
| language | English |
| last_indexed | 2024-03-08T06:52:22Z |
| publishDate | 2023-03-01 |
| publisher | Korean Spinal Neurosurgery Society |
| record_format | Article |
| series | Neurospine |
| spelling | doaj.art-c67aaf4e8bb2471696e865b6fbc51c3c2024-02-03T06:43:45ZengKorean Spinal Neurosurgery SocietyNeurospine2586-65832586-65912023-03-0120125526410.14245/ns.2244772.3861358Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control StudyYu Xiao0Bing Wang1Yulian Chen2Lingqiang Chen3Zhenkai Lou4Zhiqiang Gong5 Department of Orthopaedics, The First Affiliated Hospital of Kunming Medical University, Kunming, China Department of Orthopaedics, The First Affiliated Hospital of Kunming Medical University, Kunming, China Department of ENT, The First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, Kunming, China Department of Orthopaedics, The First Affiliated Hospital of Kunming Medical University, Kunming, China Department of Orthopaedics, The First Affiliated Hospital of Kunming Medical University, Kunming, China Department of Orthopaedics, The First Affiliated Hospital of Kunming Medical University, Kunming, ChinaObjective To identify potential risk factors for cerebrospinal fluid (CSF) leakage after craniovertebral junction (CVJ) anomaly surgery and to provide a reference for clinical practice. Methods Sixty-six patients who underwent elective CVJ anomaly surgery during a 6-year period (April 2013 to September 2019) were retrospectively included. Research data were collected from the patients’ medical records and imaging systems. Patients were divided into CSF leak and no CSF leak groups. Univariate tests were performed to identify potential risk factors. For statistically significant variables in the univariate tests, a logistic regression test was used to identify independent risk factors for CSF leakage. Results The overall prevalence of CSF leakage was 13.64%. Univariate tests showed that a basion-dental interval (BDI) > 10 mm and occipitalized atlas had significant intergroup differences (p < 0.05). Multivariate analysis indicated that a BDI > 10 mm was an independent risk factor for CSF leakage, and patients with CVJ anomalies with a BDI > 10 mm were more likely to have postoperative CSF leaks (odds ratio, 14.67; 95% confidence interval, 1.48–30.88; p = 0.004). Conclusion It is necessary to maintain vigilance during CVJ anomaly surgery in patients with a preoperative BDI > 10 mm to avoid postoperative CSF leaks.http://e-neurospine.org/upload/pdf/ns-2244772-386.pdfcraniovertebral junction anomaliescerebrospinal fluid leakrisk factorcraniovertebral junction instabilitybasion-dental interval |
| spellingShingle | Yu Xiao Bing Wang Yulian Chen Lingqiang Chen Zhenkai Lou Zhiqiang Gong Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study Neurospine craniovertebral junction anomalies cerebrospinal fluid leak risk factor craniovertebral junction instability basion-dental interval |
| title | Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study |
| title_full | Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study |
| title_fullStr | Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study |
| title_full_unstemmed | Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study |
| title_short | Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study |
| title_sort | risk factors of postoperative cerebrospinal fluid leak after craniovertebral junction anomalies surgery a case control study |
| topic | craniovertebral junction anomalies cerebrospinal fluid leak risk factor craniovertebral junction instability basion-dental interval |
| url | http://e-neurospine.org/upload/pdf/ns-2244772-386.pdf |
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