Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
The objective of this work was to study the correlation of uric acid level in blood serum and parameters of endothelial function and non-specific inflammation in adolescents with arterial hypertension considering their body weight. In the most of patients with arterial hypertension endothelial dysfu...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Zaslavsky O.Yu.
2013-08-01
|
Series: | Zdorovʹe Rebenka |
Subjects: | |
Online Access: | http://childshealth.zaslavsky.com.ua/article/view/84747 |
_version_ | 1818958225507090432 |
---|---|
author | N.M. Korenev I.N. Bessonova T.S. Vvedenskaya |
author_facet | N.M. Korenev I.N. Bessonova T.S. Vvedenskaya |
author_sort | N.M. Korenev |
collection | DOAJ |
description | The objective of this work was to study the correlation of uric acid level in blood serum and parameters of endothelial function and non-specific inflammation in adolescents with arterial hypertension considering their body weight. In the most of patients with arterial hypertension endothelial dysfunction was detected; endothelium-dependent vasodilation was more altered in the patients with obesity and especially in those with hyperuricemia. An increase in C-reactive protein serum level was mainly associated with obesity; a decrease in systolic-diastolic ratio — with hyperuricemia. |
first_indexed | 2024-12-20T11:22:22Z |
format | Article |
id | doaj.art-c67b1c0f6c0644f4b05c917bf4a4a3f0 |
institution | Directory Open Access Journal |
issn | 2224-0551 2307-1168 |
language | English |
last_indexed | 2024-12-20T11:22:22Z |
publishDate | 2013-08-01 |
publisher | Zaslavsky O.Yu. |
record_format | Article |
series | Zdorovʹe Rebenka |
spelling | doaj.art-c67b1c0f6c0644f4b05c917bf4a4a3f02022-12-21T19:42:29ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682013-08-0185.48586210.22141/2224-0551.5.48.2013.8474784747Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial HypertensionN.M. Korenev0I.N. Bessonova1T.S. Vvedenskaya2State Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivThe objective of this work was to study the correlation of uric acid level in blood serum and parameters of endothelial function and non-specific inflammation in adolescents with arterial hypertension considering their body weight. In the most of patients with arterial hypertension endothelial dysfunction was detected; endothelium-dependent vasodilation was more altered in the patients with obesity and especially in those with hyperuricemia. An increase in C-reactive protein serum level was mainly associated with obesity; a decrease in systolic-diastolic ratio — with hyperuricemia.http://childshealth.zaslavsky.com.ua/article/view/84747adolescentsarterial hypertensionhyperuricemiaendothelial dysfunction |
spellingShingle | N.M. Korenev I.N. Bessonova T.S. Vvedenskaya Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension Zdorovʹe Rebenka adolescents arterial hypertension hyperuricemia endothelial dysfunction |
title | Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension |
title_full | Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension |
title_fullStr | Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension |
title_full_unstemmed | Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension |
title_short | Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension |
title_sort | hyperuricemia in destabilization of endothelial function in adolescents with arterial hypertension |
topic | adolescents arterial hypertension hyperuricemia endothelial dysfunction |
url | http://childshealth.zaslavsky.com.ua/article/view/84747 |
work_keys_str_mv | AT nmkorenev hyperuricemiaindestabilizationofendothelialfunctioninadolescentswitharterialhypertension AT inbessonova hyperuricemiaindestabilizationofendothelialfunctioninadolescentswitharterialhypertension AT tsvvedenskaya hyperuricemiaindestabilizationofendothelialfunctioninadolescentswitharterialhypertension |