Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension

The objective of this work was to study the correlation of uric acid level in blood serum and parameters of endothelial function and non-specific inflammation in adolescents with arterial hypertension considering their body weight. In the most of patients with arterial hypertension endothelial dysfu...

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Main Authors: N.M. Korenev, I.N. Bessonova, T.S. Vvedenskaya
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2013-08-01
Series:Zdorovʹe Rebenka
Subjects:
Online Access:http://childshealth.zaslavsky.com.ua/article/view/84747
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author N.M. Korenev
I.N. Bessonova
T.S. Vvedenskaya
author_facet N.M. Korenev
I.N. Bessonova
T.S. Vvedenskaya
author_sort N.M. Korenev
collection DOAJ
description The objective of this work was to study the correlation of uric acid level in blood serum and parameters of endothelial function and non-specific inflammation in adolescents with arterial hypertension considering their body weight. In the most of patients with arterial hypertension endothelial dysfunction was detected; endothelium-dependent vasodilation was more altered in the patients with obesity and especially in those with hyperuricemia. An increase in C-reactive protein serum level was mainly associated with obesity; a decrease in systolic-diastolic ratio — with hyperuricemia.
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spelling doaj.art-c67b1c0f6c0644f4b05c917bf4a4a3f02022-12-21T19:42:29ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682013-08-0185.48586210.22141/2224-0551.5.48.2013.8474784747Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial HypertensionN.M. Korenev0I.N. Bessonova1T.S. Vvedenskaya2State Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivState Institution «Institute of Children and Adolescents Health Care of National Academy of Medical Sciences of Ukraine», KharkivThe objective of this work was to study the correlation of uric acid level in blood serum and parameters of endothelial function and non-specific inflammation in adolescents with arterial hypertension considering their body weight. In the most of patients with arterial hypertension endothelial dysfunction was detected; endothelium-dependent vasodilation was more altered in the patients with obesity and especially in those with hyperuricemia. An increase in C-reactive protein serum level was mainly associated with obesity; a decrease in systolic-diastolic ratio — with hyperuricemia.http://childshealth.zaslavsky.com.ua/article/view/84747adolescentsarterial hypertensionhyperuricemiaendothelial dysfunction
spellingShingle N.M. Korenev
I.N. Bessonova
T.S. Vvedenskaya
Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
Zdorovʹe Rebenka
adolescents
arterial hypertension
hyperuricemia
endothelial dysfunction
title Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
title_full Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
title_fullStr Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
title_full_unstemmed Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
title_short Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
title_sort hyperuricemia in destabilization of endothelial function in adolescents with arterial hypertension
topic adolescents
arterial hypertension
hyperuricemia
endothelial dysfunction
url http://childshealth.zaslavsky.com.ua/article/view/84747
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AT inbessonova hyperuricemiaindestabilizationofendothelialfunctioninadolescentswitharterialhypertension
AT tsvvedenskaya hyperuricemiaindestabilizationofendothelialfunctioninadolescentswitharterialhypertension