Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair
Background Acute kidney injury (AKI) is one of the most common and serious complications in patients with type B aortic dissection (TBAD). This study aimed at investigating the incidence and risk factors of in-hospital AKI in TBAD patients involving the renal artery who underwent thoracic endovascul...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Renal Failure |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/0886022X.2021.1949349 |
| _version_ | 1798031764344537088 |
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| author | Xiuping An Xi Guo Nan Ye Weijing Bian Xiaofeng Han Guoqin Wang Hong Cheng |
| author_facet | Xiuping An Xi Guo Nan Ye Weijing Bian Xiaofeng Han Guoqin Wang Hong Cheng |
| author_sort | Xiuping An |
| collection | DOAJ |
| description | Background Acute kidney injury (AKI) is one of the most common and serious complications in patients with type B aortic dissection (TBAD). This study aimed at investigating the incidence and risk factors of in-hospital AKI in TBAD patients involving the renal artery who underwent thoracic endovascular aortic repair (TEVAR) only. Methods A total of 256 patients who were diagnosed as TBAD combined with renal artery involvement were included in this retrospective study. All patients were divided into the AKI group and the non-AKI group according to the KDIGO criteria. The risk factors for AKI were identified using a multivariate logistic regression model. Results A total of 256 patients were included in this study, and the incidence of AKI was 18% (46/256). Patients in the AKI group were more likely to have a higher proportion of the youth, a higher level of body mass index, and a shorter time from onset to admission. Multivariate logistic regression analysis revealed that the youth (age ≤40 years) (OR: 2.853, 95%CI: 1.061–7.668, p = .038) were prone to AKI, and lower estimated glomerular filtration rate (eGFR) (OR: 1.526, per 15-ml/min/1.73 m2 decrease, 95%CI: 1.114–2.092; p = .009), higher diastolic blood pressure (DBP) (OR: 1.418, per 10-mmHg increase; 95%CI: 1.070–1.879; p = .015), and fasting blood glucose (FBG) ≥7 mmol/L on admission (OR: 2.592; 95%CI: 1.299–5.174; p = .007) were independent risk factors for AKI. Conclusions Higher incidence of AKI had been perceived in this study, most of them were young and middle-aged patients. Renopreventive measures should be considered in those high-risk patients with younger age, lower eGFR, higher DBP, and higher FBG on admission. |
| first_indexed | 2024-04-11T20:02:53Z |
| format | Article |
| id | doaj.art-c682c2dab5b745cea398ae5bcdff0c65 |
| institution | Directory Open Access Journal |
| issn | 0886-022X 1525-6049 |
| language | English |
| last_indexed | 2024-04-11T20:02:53Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj.art-c682c2dab5b745cea398ae5bcdff0c652022-12-22T04:05:32ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492021-01-014311130113610.1080/0886022X.2021.19493491949349Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repairXiuping An0Xi Guo1Nan Ye2Weijing Bian3Xiaofeng Han4Guoqin Wang5Hong Cheng6Division of Nephrology, Beijing AnZhen Hospital, Capital Medical UniversityDivision of Diagnostic and Interventional Radiology, Beijing AnZhen Hospital, Capital Medical UniversityDivision of Nephrology, Beijing AnZhen Hospital, Capital Medical UniversityDivision of Nephrology, Beijing AnZhen Hospital, Capital Medical UniversityDivision of Diagnostic and Interventional Radiology, Beijing AnZhen Hospital, Capital Medical UniversityDivision of Nephrology, Beijing AnZhen Hospital, Capital Medical UniversityDivision of Nephrology, Beijing AnZhen Hospital, Capital Medical UniversityBackground Acute kidney injury (AKI) is one of the most common and serious complications in patients with type B aortic dissection (TBAD). This study aimed at investigating the incidence and risk factors of in-hospital AKI in TBAD patients involving the renal artery who underwent thoracic endovascular aortic repair (TEVAR) only. Methods A total of 256 patients who were diagnosed as TBAD combined with renal artery involvement were included in this retrospective study. All patients were divided into the AKI group and the non-AKI group according to the KDIGO criteria. The risk factors for AKI were identified using a multivariate logistic regression model. Results A total of 256 patients were included in this study, and the incidence of AKI was 18% (46/256). Patients in the AKI group were more likely to have a higher proportion of the youth, a higher level of body mass index, and a shorter time from onset to admission. Multivariate logistic regression analysis revealed that the youth (age ≤40 years) (OR: 2.853, 95%CI: 1.061–7.668, p = .038) were prone to AKI, and lower estimated glomerular filtration rate (eGFR) (OR: 1.526, per 15-ml/min/1.73 m2 decrease, 95%CI: 1.114–2.092; p = .009), higher diastolic blood pressure (DBP) (OR: 1.418, per 10-mmHg increase; 95%CI: 1.070–1.879; p = .015), and fasting blood glucose (FBG) ≥7 mmol/L on admission (OR: 2.592; 95%CI: 1.299–5.174; p = .007) were independent risk factors for AKI. Conclusions Higher incidence of AKI had been perceived in this study, most of them were young and middle-aged patients. Renopreventive measures should be considered in those high-risk patients with younger age, lower eGFR, higher DBP, and higher FBG on admission.http://dx.doi.org/10.1080/0886022X.2021.1949349acute kidney injurytype b aortic dissectiontevarrisk factors |
| spellingShingle | Xiuping An Xi Guo Nan Ye Weijing Bian Xiaofeng Han Guoqin Wang Hong Cheng Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair Renal Failure acute kidney injury type b aortic dissection tevar risk factors |
| title | Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair |
| title_full | Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair |
| title_fullStr | Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair |
| title_full_unstemmed | Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair |
| title_short | Risk factors of acute kidney injury in patients with Stanford type B aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair |
| title_sort | risk factors of acute kidney injury in patients with stanford type b aortic dissection involving the renal artery who underwent thoracic endovascular aortic repair |
| topic | acute kidney injury type b aortic dissection tevar risk factors |
| url | http://dx.doi.org/10.1080/0886022X.2021.1949349 |
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