Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?

So far, there has been no generally accepted diagnostic and therapeutic algorithm for patients with embolic stroke of undetermined source (ESUS). As recent clinical trials on secondary stroke prevention in ESUS did not support the use of oral anticoagulation and the concept of ESUS comprises heterog...

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Main Authors: Katharina Feil, Johanna Heinrich, Aenne S. von Falkenhausen, Regina Becker, Clemens Küpper, Katharina Müller, Dennis C. Thunstedt, Moritz F. Sinner, Stefan Kääb, Lars Kellert
Format: Article
Language:English
Published: Karger Publishers 2020-01-01
Series:Case Reports in Neurology
Subjects:
Online Access:https://www.karger.com/Article/FullText/505180
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author Katharina Feil
Johanna Heinrich
Aenne S. von Falkenhausen
Regina Becker
Clemens Küpper
Katharina Müller
Dennis C. Thunstedt
Moritz F. Sinner
Stefan Kääb
Lars Kellert
author_facet Katharina Feil
Johanna Heinrich
Aenne S. von Falkenhausen
Regina Becker
Clemens Küpper
Katharina Müller
Dennis C. Thunstedt
Moritz F. Sinner
Stefan Kääb
Lars Kellert
author_sort Katharina Feil
collection DOAJ
description So far, there has been no generally accepted diagnostic and therapeutic algorithm for patients with embolic stroke of undetermined source (ESUS). As recent clinical trials on secondary stroke prevention in ESUS did not support the use of oral anticoagulation and the concept of ESUS comprises heterogeneous subgroups of patients, including a wide age range, concomitant patent foramen ovale (PFO), variable cardiovascular risk factors as well as a variable probability for atrial fibrillation (AF), an individualized clinical approach is needed. In this context, we here present a case of recurrent stroke in a young patient with ESUS and PFO. During treatment according to our Catch-up-ESUS registry study, prolonged cardiac monitoring diagnosed AF, and PFO closure was omitted.
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spelling doaj.art-c68717d6aa5c43ba93e0479e21c837a92022-12-21T17:30:29ZengKarger PublishersCase Reports in Neurology1662-680X2020-01-01121454910.1159/000505180505180Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?Katharina FeilJohanna HeinrichAenne S. von FalkenhausenRegina BeckerClemens KüpperKatharina MüllerDennis C. ThunstedtMoritz F. SinnerStefan KääbLars KellertSo far, there has been no generally accepted diagnostic and therapeutic algorithm for patients with embolic stroke of undetermined source (ESUS). As recent clinical trials on secondary stroke prevention in ESUS did not support the use of oral anticoagulation and the concept of ESUS comprises heterogeneous subgroups of patients, including a wide age range, concomitant patent foramen ovale (PFO), variable cardiovascular risk factors as well as a variable probability for atrial fibrillation (AF), an individualized clinical approach is needed. In this context, we here present a case of recurrent stroke in a young patient with ESUS and PFO. During treatment according to our Catch-up-ESUS registry study, prolonged cardiac monitoring diagnosed AF, and PFO closure was omitted.https://www.karger.com/Article/FullText/505180embolic stroke of undetermined sourcepatent foramen ovale closureatrial fibrillationinsertable cardiac monitor
spellingShingle Katharina Feil
Johanna Heinrich
Aenne S. von Falkenhausen
Regina Becker
Clemens Küpper
Katharina Müller
Dennis C. Thunstedt
Moritz F. Sinner
Stefan Kääb
Lars Kellert
Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?
Case Reports in Neurology
embolic stroke of undetermined source
patent foramen ovale closure
atrial fibrillation
insertable cardiac monitor
title Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?
title_full Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?
title_fullStr Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?
title_full_unstemmed Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?
title_short Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?
title_sort recurrent stroke in a young patient with embolic stroke of undetermined source and patent foramen ovale quo vadis
topic embolic stroke of undetermined source
patent foramen ovale closure
atrial fibrillation
insertable cardiac monitor
url https://www.karger.com/Article/FullText/505180
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