The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease
Aim: The aim of this study was to assess the prevalence of micro- and macrovascular disease in Egyptian patients with diabetes mellitus (DM) and peripheral arterial disease (PAD). Methods: The study included 161 Egyptian patients with DM and PAD (91.3% had type 2 DM and 67.1% were females). Mean dia...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Greater Baltimore Medical Center
2021-03-01
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| Series: | Journal of Community Hospital Internal Medicine Perspectives |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20009666.2021.1877906 |
| _version_ | 1797968515438739456 |
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| author | Maha Assem Shrook Mousa Alaa Abdelhamid Samar Amin Ayman Elsamadony Eman El-Sebaee Aasem Saif Shereen Elsawy |
| author_facet | Maha Assem Shrook Mousa Alaa Abdelhamid Samar Amin Ayman Elsamadony Eman El-Sebaee Aasem Saif Shereen Elsawy |
| author_sort | Maha Assem |
| collection | DOAJ |
| description | Aim: The aim of this study was to assess the prevalence of micro- and macrovascular disease in Egyptian patients with diabetes mellitus (DM) and peripheral arterial disease (PAD). Methods: The study included 161 Egyptian patients with DM and PAD (91.3% had type 2 DM and 67.1% were females). Mean diabetes duration was 14.2 ± 5.2 years. Full history, clinical and fundus examination as well as laboratory investigations were done. PAD was diagnosed through assessment of ankle/brachial index (ABI) by Doppler ultrasonography. Results: ABI was <0.9 in 33.5% and >1.3 in 66.5% of patients. A significant positive correlation was found between abnormal ABI and diabetes duration, ischemic heart disease (IHD), diabetic retinopathy and neuropathy, foot ulcers, elevated blood pressure (BP), creatinine, urine albumin/creatinine ratio (ACR) and triglycerides and a significant negative correlation with HDL. Multivariate regression analysis revealed that the independent predictors for PAD in patients with ABI< 0.9 were neuropathy, creatinine, triglyceride, LDL, urine ACR and low HDL, and in patients with ABI >1.3 were IHD, neuropathy, elevated diastolic BP and triglyceride. Conclusion: The risk of micro- and macrovascular disease is high in Egyptian patients with diabetes and PAD. Early diagnosis and good control of risk factors could reduce PAD progression. |
| first_indexed | 2024-04-11T02:46:57Z |
| format | Article |
| id | doaj.art-c68bc9cf86a34216ab0ca4a935025080 |
| institution | Directory Open Access Journal |
| issn | 2000-9666 |
| language | English |
| last_indexed | 2024-04-11T02:46:57Z |
| publishDate | 2021-03-01 |
| publisher | Greater Baltimore Medical Center |
| record_format | Article |
| series | Journal of Community Hospital Internal Medicine Perspectives |
| spelling | doaj.art-c68bc9cf86a34216ab0ca4a9350250802023-01-02T17:40:58ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-03-0111221621910.1080/20009666.2021.18779061877906The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial diseaseMaha Assem0Shrook Mousa1Alaa Abdelhamid2Samar Amin3Ayman Elsamadony4Eman El-Sebaee5Aasem Saif6Shereen Elsawy7Cairo UniversityCairo UniversityCairo UniversityCairo UniversityCairo UniversityCairo UniversityCairo UniversityCairo UniversityAim: The aim of this study was to assess the prevalence of micro- and macrovascular disease in Egyptian patients with diabetes mellitus (DM) and peripheral arterial disease (PAD). Methods: The study included 161 Egyptian patients with DM and PAD (91.3% had type 2 DM and 67.1% were females). Mean diabetes duration was 14.2 ± 5.2 years. Full history, clinical and fundus examination as well as laboratory investigations were done. PAD was diagnosed through assessment of ankle/brachial index (ABI) by Doppler ultrasonography. Results: ABI was <0.9 in 33.5% and >1.3 in 66.5% of patients. A significant positive correlation was found between abnormal ABI and diabetes duration, ischemic heart disease (IHD), diabetic retinopathy and neuropathy, foot ulcers, elevated blood pressure (BP), creatinine, urine albumin/creatinine ratio (ACR) and triglycerides and a significant negative correlation with HDL. Multivariate regression analysis revealed that the independent predictors for PAD in patients with ABI< 0.9 were neuropathy, creatinine, triglyceride, LDL, urine ACR and low HDL, and in patients with ABI >1.3 were IHD, neuropathy, elevated diastolic BP and triglyceride. Conclusion: The risk of micro- and macrovascular disease is high in Egyptian patients with diabetes and PAD. Early diagnosis and good control of risk factors could reduce PAD progression.http://dx.doi.org/10.1080/20009666.2021.1877906peripheral arterial diseasediabetesmicrovascularmacrovascularankle/brachial index |
| spellingShingle | Maha Assem Shrook Mousa Alaa Abdelhamid Samar Amin Ayman Elsamadony Eman El-Sebaee Aasem Saif Shereen Elsawy The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease Journal of Community Hospital Internal Medicine Perspectives peripheral arterial disease diabetes microvascular macrovascular ankle/brachial index |
| title | The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease |
| title_full | The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease |
| title_fullStr | The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease |
| title_full_unstemmed | The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease |
| title_short | The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease |
| title_sort | risk of micro and macrovascular disease in egyptian patients with diabetes and peripheral arterial disease |
| topic | peripheral arterial disease diabetes microvascular macrovascular ankle/brachial index |
| url | http://dx.doi.org/10.1080/20009666.2021.1877906 |
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