Effects of partial penectomy for penile cancer on sexual function: A systematic review.
Penile cancer is a rare but debilitating condition, which often requires aggressive treatment. Partial penectomy is considered as a treatment option when a sufficient portion of the penile shaft can be maintained to preserve functionality. This systematic review, which followed the PRIMSA guidelines...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0274914 |
| _version_ | 1811345331545178112 |
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| author | Eleanor Whyte Alexandra Sutcliffe Philip Keegan Tom Clifford Jamie Matu Oliver M Shannon Alex Griffiths |
| author_facet | Eleanor Whyte Alexandra Sutcliffe Philip Keegan Tom Clifford Jamie Matu Oliver M Shannon Alex Griffiths |
| author_sort | Eleanor Whyte |
| collection | DOAJ |
| description | Penile cancer is a rare but debilitating condition, which often requires aggressive treatment. Partial penectomy is considered as a treatment option when a sufficient portion of the penile shaft can be maintained to preserve functionality. This systematic review, which followed the PRIMSA guidelines, aimed to evaluate the effects of partial penectomy for penile cancer on sexual function-the maintenance of which is often a priority in patient groups-and to identify potential factors which may moderate these effects. A systematic search of PubMed, The Cochrane Library, and Open Grey as well as MEDLINE, CINAHL and Open Dissertations via EBSCOhost was conducted from inception through to 24th March, 2022. Studies were required to include adults aged ≥18 years who had undergone partial penectomy for the treatment of penile cancer, with a quantitative measure of sexual function available pre- and post-surgery. Four eligible articles were identified for inclusion in this review, three of which reported a decrease in sexual function pre- to post-surgery across all domains of the International Index of Erectile Function (IIEF) questionnaire (erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction). Conversely, one study reported an increase in sexual function across IIEF domains, except for orgasmic function, which decreased, pre- to post-surgery. Greater penile length was associated with higher post-operative sexual function, whilst increasing age and higher anxiety levels were associated with lower post-operative sexual function levels in one study. Despite the overall drop in sexual function, many patients were still able to maintain satisfactory sex lives following partial penectomy. Given the limited research in this area and small sample sizes across studies, additional well-controlled investigations are warranted to provide further evidence on the effects of partial penectomy for penile cancer on sexual function. |
| first_indexed | 2024-04-13T20:02:28Z |
| format | Article |
| id | doaj.art-c68be75aecae4b74b81ff1511eb7b5e4 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T20:02:28Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c68be75aecae4b74b81ff1511eb7b5e42022-12-22T02:32:10ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01179e027491410.1371/journal.pone.0274914Effects of partial penectomy for penile cancer on sexual function: A systematic review.Eleanor WhyteAlexandra SutcliffePhilip KeeganTom CliffordJamie MatuOliver M ShannonAlex GriffithsPenile cancer is a rare but debilitating condition, which often requires aggressive treatment. Partial penectomy is considered as a treatment option when a sufficient portion of the penile shaft can be maintained to preserve functionality. This systematic review, which followed the PRIMSA guidelines, aimed to evaluate the effects of partial penectomy for penile cancer on sexual function-the maintenance of which is often a priority in patient groups-and to identify potential factors which may moderate these effects. A systematic search of PubMed, The Cochrane Library, and Open Grey as well as MEDLINE, CINAHL and Open Dissertations via EBSCOhost was conducted from inception through to 24th March, 2022. Studies were required to include adults aged ≥18 years who had undergone partial penectomy for the treatment of penile cancer, with a quantitative measure of sexual function available pre- and post-surgery. Four eligible articles were identified for inclusion in this review, three of which reported a decrease in sexual function pre- to post-surgery across all domains of the International Index of Erectile Function (IIEF) questionnaire (erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction). Conversely, one study reported an increase in sexual function across IIEF domains, except for orgasmic function, which decreased, pre- to post-surgery. Greater penile length was associated with higher post-operative sexual function, whilst increasing age and higher anxiety levels were associated with lower post-operative sexual function levels in one study. Despite the overall drop in sexual function, many patients were still able to maintain satisfactory sex lives following partial penectomy. Given the limited research in this area and small sample sizes across studies, additional well-controlled investigations are warranted to provide further evidence on the effects of partial penectomy for penile cancer on sexual function.https://doi.org/10.1371/journal.pone.0274914 |
| spellingShingle | Eleanor Whyte Alexandra Sutcliffe Philip Keegan Tom Clifford Jamie Matu Oliver M Shannon Alex Griffiths Effects of partial penectomy for penile cancer on sexual function: A systematic review. PLoS ONE |
| title | Effects of partial penectomy for penile cancer on sexual function: A systematic review. |
| title_full | Effects of partial penectomy for penile cancer on sexual function: A systematic review. |
| title_fullStr | Effects of partial penectomy for penile cancer on sexual function: A systematic review. |
| title_full_unstemmed | Effects of partial penectomy for penile cancer on sexual function: A systematic review. |
| title_short | Effects of partial penectomy for penile cancer on sexual function: A systematic review. |
| title_sort | effects of partial penectomy for penile cancer on sexual function a systematic review |
| url | https://doi.org/10.1371/journal.pone.0274914 |
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