CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel

CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel

Abstract Background Oral squamous cell carcinoma (OSCC) is usually diagnosed at an advanced stage and is commonly preceded by oral premalignant lesions. The mortality rates have remained unchanged (50% within 5 years after diagnosis), and it is related to tobacco smoking and alcohol intake. Novel mo...

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書目詳細資料
Main Authors: Luca Morandi, Davide Gissi, Achille Tarsitano, Sofia Asioli, Andrea Gabusi, Claudio Marchetti, Lucio Montebugnoli, Maria Pia Foschini
格式: Article
語言:English
出版: BMC 2017-08-01
叢編:Clinical Epigenetics
主題:
Bisulfite sequencing
Quantitative DNA methylation analysis
Algorithm
Oral brushing
Oral squamous cell carcinoma
在線閱讀:http://link.springer.com/article/10.1186/s13148-017-0386-7

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