Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers

Background: Smokers are known to have a higher risk of erectile dysfunction. We examined how daily consumption of low-dose tadalafil affected erectile function and circulation in smokers and assessed the medication safety. Methods: Men aged over 20 years with current smoking status were selected to...

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Main Authors: David Samuel Kwak, Byung Wook Yoo
Format: Article
Language:English
Published: MRE Press 2022-07-01
Series:Journal of Men's Health
Subjects:
Online Access:https://www.imrpress.com/journal/JOMH/18/7/10.31083/j.jomh1807150
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author David Samuel Kwak
Byung Wook Yoo
author_facet David Samuel Kwak
Byung Wook Yoo
author_sort David Samuel Kwak
collection DOAJ
description Background: Smokers are known to have a higher risk of erectile dysfunction. We examined how daily consumption of low-dose tadalafil affected erectile function and circulation in smokers and assessed the medication safety. Methods: Men aged over 20 years with current smoking status were selected to complete four weeks of treatment with 5 mg tadalafil daily. Erectile function was measured using the International Index of Erectile Function (IIEF), and additional tests included measuring various serum parameters, electrocardiogram, and nail capillary blood flow. Results: The IIEF scores, capillary blood flow, and serum liver function enzyme levels significantly improved. There were no reported adverse side effects. Conclusions: Smokers who were administered 5 mg tadalafil daily for four weeks had improved International Index of Erectile Function scores, dilated capillary vessels, and improved blood liver function enzyme levels; proving not only safety of usage and its effectiveness but also possible features that can indicate usages of the drug in other purposes.
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spelling doaj.art-c68feac538d24ffc8f234db6d179b95a2024-02-03T10:53:25ZengMRE PressJournal of Men's Health1875-68592022-07-0118715010.31083/j.jomh1807150S1875-6867(22)00399-2Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in SmokersDavid Samuel Kwak0Byung Wook Yoo1Department of Family Medicine, Soonchunhyang University Hospital Seoul, 04401 Seoul, Republic of KoreaDepartment of Family Medicine, Soonchunhyang University Hospital Seoul, 04401 Seoul, Republic of KoreaBackground: Smokers are known to have a higher risk of erectile dysfunction. We examined how daily consumption of low-dose tadalafil affected erectile function and circulation in smokers and assessed the medication safety. Methods: Men aged over 20 years with current smoking status were selected to complete four weeks of treatment with 5 mg tadalafil daily. Erectile function was measured using the International Index of Erectile Function (IIEF), and additional tests included measuring various serum parameters, electrocardiogram, and nail capillary blood flow. Results: The IIEF scores, capillary blood flow, and serum liver function enzyme levels significantly improved. There were no reported adverse side effects. Conclusions: Smokers who were administered 5 mg tadalafil daily for four weeks had improved International Index of Erectile Function scores, dilated capillary vessels, and improved blood liver function enzyme levels; proving not only safety of usage and its effectiveness but also possible features that can indicate usages of the drug in other purposes.https://www.imrpress.com/journal/JOMH/18/7/10.31083/j.jomh1807150erectile dysfunctionliver functionsmokerstadalafil
spellingShingle David Samuel Kwak
Byung Wook Yoo
Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers
Journal of Men's Health
erectile dysfunction
liver function
smokers
tadalafil
title Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers
title_full Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers
title_fullStr Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers
title_full_unstemmed Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers
title_short Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers
title_sort daily dose of 5 mg tadalafil safely improves erectile function and liver function enzymes in smokers
topic erectile dysfunction
liver function
smokers
tadalafil
url https://www.imrpress.com/journal/JOMH/18/7/10.31083/j.jomh1807150
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