CD73 regulates zoledronate-induced lymphocyte infiltration in triple-negative breast cancer tumors and lung metastases

CD73 regulates zoledronate-induced lymphocyte infiltration in triple-negative breast cancer tumors and lung metastases

IntroductionBisphosphonates (BPs) are bone-protecting osteoclast inhibitors, typically used in the treatment of osteoporosis and skeletal complications of malignancies. When given in the adjuvant setting, these drugs may also prevent relapses and prolong overall survival in early breast cancer (EBC)...

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Bibliographic Details
Main Authors: Nataliia Petruk, Arafat Siddiqui, Sina Tadayon, Jorma Määttä, Pieta K. Mattila, Arja Jukkola, Jouko Sandholm, Katri S. Selander
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
CD73
TNBC
zoledronate
tumor growth
tumor-infiltrating lymphocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1179022/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1179022/full

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