A novel expression system for production of soluble prion proteins in E. coli

<p>Abstract</p> <p>Expression of eukaryotic proteins in <it>Escherichia coli </it>is challenging, especially when they contain disulfide bonds. Since the discovery of the prion protein (PrP) and its role in transmissible spongiform encephalopathies, the need to obtain l...

Full description

Bibliographic Details
Main Authors: Abskharon Romany NN, Ramboarina Stephanie, El Hassan Hassan, Gad Wael, Apostol Marcin I, Giachin Gabriele, Legname Giuseppe, Steyaert Jan, Messens Joris, Soror Sameh H, Wohlkonig Alexandre
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/11/1/6