A novel expression system for production of soluble prion proteins in E. coli

A novel expression system for production of soluble prion proteins in E. coli

<p>Abstract</p> <p>Expression of eukaryotic proteins in <it>Escherichia coli </it>is challenging, especially when they contain disulfide bonds. Since the discovery of the prion protein (PrP) and its role in transmissible spongiform encephalopathies, the need to obtain l...

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Bibliographic Details
Main Authors: Abskharon Romany NN, Ramboarina Stephanie, El Hassan Hassan, Gad Wael, Apostol Marcin I, Giachin Gabriele, Legname Giuseppe, Steyaert Jan, Messens Joris, Soror Sameh H, Wohlkonig Alexandre
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/11/1/6

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