Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report
Extraintestinal manifestations (EIMs) are observed in 15–20% of patients with inflammatory bowel disease (IBD). One of the rare EIMs is myocarditis, the incidence of which is estimated at around 1%. The main cause of myocarditis is a viral infection. Other causes include autoimmune diseases and drug...
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| Format: | Article |
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MDPI AG
2022-01-01
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| Series: | Pediatric Reports |
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| Online Access: | https://www.mdpi.com/2036-7503/14/1/5 |
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| author | Joanna Ryzko Katarzyna Zdanowicz Dariusz Marek Lebensztejn Urszula Daniluk |
| author_facet | Joanna Ryzko Katarzyna Zdanowicz Dariusz Marek Lebensztejn Urszula Daniluk |
| author_sort | Joanna Ryzko |
| collection | DOAJ |
| description | Extraintestinal manifestations (EIMs) are observed in 15–20% of patients with inflammatory bowel disease (IBD). One of the rare EIMs is myocarditis, the incidence of which is estimated at around 1%. The main cause of myocarditis is a viral infection. Other causes include autoimmune diseases and drug complications (sulfasalazine, mesalazine). We present the case of an 11-year-old girl with Crohn’s disease (CD) with EIMs, manifested as hip joint inflammation and erythema nodosum. At the same time, the symptoms of myopericarditis appeared with changes in electrocardiogram (ECG), echocardiography and high troponin I concentration. Therapy with corticosteroids resulted in the resolution of skin lesions and cardiological symptoms. Systemic connective tissue diseases, viral and bacterial infections were excluded in the differential diagnosis. The suspicion of mesalazine-induced EIMs was also ruled out as the symptoms resolved despite continued therapy with mesalazine. No further recurrences of myopericarditis were observed. |
| first_indexed | 2024-03-09T13:02:06Z |
| format | Article |
| id | doaj.art-c6964d9634dd4f09b7b52d2d2c1eb8d4 |
| institution | Directory Open Access Journal |
| issn | 2036-7503 |
| language | English |
| last_indexed | 2024-03-09T13:02:06Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pediatric Reports |
| spelling | doaj.art-c6964d9634dd4f09b7b52d2d2c1eb8d42023-11-30T21:53:26ZengMDPI AGPediatric Reports2036-75032022-01-01141263110.3390/pediatric14010005Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case ReportJoanna Ryzko0Katarzyna Zdanowicz1Dariusz Marek Lebensztejn2Urszula Daniluk3Department of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, Waszyngtona St. 17, 15-274 Białystok, PolandDepartment of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, Waszyngtona St. 17, 15-274 Białystok, PolandDepartment of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, Waszyngtona St. 17, 15-274 Białystok, PolandDepartment of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, Waszyngtona St. 17, 15-274 Białystok, PolandExtraintestinal manifestations (EIMs) are observed in 15–20% of patients with inflammatory bowel disease (IBD). One of the rare EIMs is myocarditis, the incidence of which is estimated at around 1%. The main cause of myocarditis is a viral infection. Other causes include autoimmune diseases and drug complications (sulfasalazine, mesalazine). We present the case of an 11-year-old girl with Crohn’s disease (CD) with EIMs, manifested as hip joint inflammation and erythema nodosum. At the same time, the symptoms of myopericarditis appeared with changes in electrocardiogram (ECG), echocardiography and high troponin I concentration. Therapy with corticosteroids resulted in the resolution of skin lesions and cardiological symptoms. Systemic connective tissue diseases, viral and bacterial infections were excluded in the differential diagnosis. The suspicion of mesalazine-induced EIMs was also ruled out as the symptoms resolved despite continued therapy with mesalazine. No further recurrences of myopericarditis were observed.https://www.mdpi.com/2036-7503/14/1/5Crohn’s diseaseextraintestinal manifestationsmyocarditischildren |
| spellingShingle | Joanna Ryzko Katarzyna Zdanowicz Dariusz Marek Lebensztejn Urszula Daniluk Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report Pediatric Reports Crohn’s disease extraintestinal manifestations myocarditis children |
| title | Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report |
| title_full | Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report |
| title_fullStr | Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report |
| title_full_unstemmed | Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report |
| title_short | Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report |
| title_sort | successful treatment with corticosteroids in an 11 year old patient with crohn s disease and myopericarditis case report |
| topic | Crohn’s disease extraintestinal manifestations myocarditis children |
| url | https://www.mdpi.com/2036-7503/14/1/5 |
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