Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review

Objective: Coriander (Coriandrum sativum L.) is an annual herb belonging to the Apiaceae (Umbellifera) family that is used as food additives traditionally. This plant is called “Geshniz” in Persian and is native to Mediterranean regions but it is currently cultivated in several countries. All parts...

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Main Authors: Mahmoud Hosseini, Mohammad Hossein Boskabady, Mohammad Reza khazdair
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-09-01
Series:Avicenna Journal of Phytomedicine
Subjects:
Online Access:https://ajp.mums.ac.ir/article_18001_c1de9eee9b56b0c27a5cfff875c4f8c2.pdf
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author Mahmoud Hosseini
Mohammad Hossein Boskabady
Mohammad Reza khazdair
author_facet Mahmoud Hosseini
Mohammad Hossein Boskabady
Mohammad Reza khazdair
author_sort Mahmoud Hosseini
collection DOAJ
description Objective: Coriander (Coriandrum sativum L.) is an annual herb belonging to the Apiaceae (Umbellifera) family that is used as food additives traditionally. This plant is called “Geshniz” in Persian and is native to Mediterranean regions but it is currently cultivated in several countries. All parts of coriander are edible and have been traditionally used to treat different disorders, including digestive problems, flatulence, diarrhea, colic and other gastrointestinal diseases. Materials and Methods: The databases PubMed, Web of Science, Google Scholar and Scopus were considered. The search terms were “Coriandrum sativum” or “linalool” and “anti-anxiety”, “sedative”, “antioxidant effect”, “anticonvulsant” and “neuroprotective effect”. Results: Antioxidant, diuretic, cholesterol lowering, anxiolytic, sedative-hypnotic and anticonvulsant activities were reported for the seeds and leaves of the plant. Furthermore, linalool as the main component of coriander has different neuropharmacological effects, including anti-anxiety, sedative, anticonvulsant and anti-Alzheimer’s disease activities. Conclusion: Various neuropharmacological effects of C. sativum and its component which have antioxidant and anti-inflammatory effects, have been summarized in the current review article.
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spelling doaj.art-c697957d41ab41298177c6e41c544fc92022-12-21T22:26:16ZengMashhad University of Medical SciencesAvicenna Journal of Phytomedicine2228-79302228-79492021-09-0111543645010.22038/ajp.2021.55681.278618001Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A reviewMahmoud Hosseini0Mohammad Hossein Boskabady1Mohammad Reza khazdair2Division of Neurocognitive Sciences, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, IranApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, IranCardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.Objective: Coriander (Coriandrum sativum L.) is an annual herb belonging to the Apiaceae (Umbellifera) family that is used as food additives traditionally. This plant is called “Geshniz” in Persian and is native to Mediterranean regions but it is currently cultivated in several countries. All parts of coriander are edible and have been traditionally used to treat different disorders, including digestive problems, flatulence, diarrhea, colic and other gastrointestinal diseases. Materials and Methods: The databases PubMed, Web of Science, Google Scholar and Scopus were considered. The search terms were “Coriandrum sativum” or “linalool” and “anti-anxiety”, “sedative”, “antioxidant effect”, “anticonvulsant” and “neuroprotective effect”. Results: Antioxidant, diuretic, cholesterol lowering, anxiolytic, sedative-hypnotic and anticonvulsant activities were reported for the seeds and leaves of the plant. Furthermore, linalool as the main component of coriander has different neuropharmacological effects, including anti-anxiety, sedative, anticonvulsant and anti-Alzheimer’s disease activities. Conclusion: Various neuropharmacological effects of C. sativum and its component which have antioxidant and anti-inflammatory effects, have been summarized in the current review article.https://ajp.mums.ac.ir/article_18001_c1de9eee9b56b0c27a5cfff875c4f8c2.pdfcoriandrum sativum lneuro-pharmacological effectsmemory impairmentlinalool
spellingShingle Mahmoud Hosseini
Mohammad Hossein Boskabady
Mohammad Reza khazdair
Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review
Avicenna Journal of Phytomedicine
coriandrum sativum l
neuro-pharmacological effects
memory impairment
linalool
title Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review
title_full Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review
title_fullStr Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review
title_full_unstemmed Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review
title_short Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review
title_sort neuroprotective effects of coriandrum sativum and its constituent linalool a review
topic coriandrum sativum l
neuro-pharmacological effects
memory impairment
linalool
url https://ajp.mums.ac.ir/article_18001_c1de9eee9b56b0c27a5cfff875c4f8c2.pdf
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AT mohammadhosseinboskabady neuroprotectiveeffectsofcoriandrumsativumanditsconstituentlinaloolareview
AT mohammadrezakhazdair neuroprotectiveeffectsofcoriandrumsativumanditsconstituentlinaloolareview