Decrease in proportion of CD19+ CD24(hi) CD27+ B cells and impairment of their suppressive function in Graves' disease.

IL-10-producing B cells (B10 cells) have been shown to play a suppressive role in the peripheral blood of humans, with their numbers and function altered in several autoimmune diseases. However, the role of B10 cells in Graves' disease (GD) remains unknown. In this study, we demonstrated that B...

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Bibliographic Details
Main Authors: Bingbing Zha, Luman Wang, Xiaoming Liu, Jun Liu, Zaoping Chen, Jiong Xu, Li Sheng, Yiming Li, Yiwei Chu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3506658?pdf=render