Multicentric Reticulohistiocytosis–A rare and disabling disease
Key Clinical Message Multicentric reticulohistiocytosis is a rare multisystemic condition associated with papulonodular skin lesions, severe arthritis and malignancy. Histopathology shows histiocytes containing abundant eosinophilic ground glass cytoplasm and multinucleated giant cells. Early recogn...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-09-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7846 |
| _version_ | 1797655198683889664 |
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| author | Omowunmi Ashaolu Selwyn Ng Shaun Smale Jenny Hughes |
| author_facet | Omowunmi Ashaolu Selwyn Ng Shaun Smale Jenny Hughes |
| author_sort | Omowunmi Ashaolu |
| collection | DOAJ |
| description | Key Clinical Message Multicentric reticulohistiocytosis is a rare multisystemic condition associated with papulonodular skin lesions, severe arthritis and malignancy. Histopathology shows histiocytes containing abundant eosinophilic ground glass cytoplasm and multinucleated giant cells. Early recognition, age‐appropriate malignancy work‐up and treatment is important to prevent impairment of daily life activity. |
| first_indexed | 2024-03-11T17:10:43Z |
| format | Article |
| id | doaj.art-c69a597775ac4009a960b22abec2189d |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-11T17:10:43Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-c69a597775ac4009a960b22abec2189d2023-10-20T06:16:21ZengWileyClinical Case Reports2050-09042023-09-01119n/an/a10.1002/ccr3.7846Multicentric Reticulohistiocytosis–A rare and disabling diseaseOmowunmi Ashaolu0Selwyn Ng1Shaun Smale2Jenny Hughes3Department of Dermatology Princess of Wales Hospital Bridgend UKDepartment of Histopathology Morriston Hospital Swansea UKDepartment of Rheumatology Princess of Wales Hospital Bridgend UKDepartment of Dermatology Princess of Wales Hospital Bridgend UKKey Clinical Message Multicentric reticulohistiocytosis is a rare multisystemic condition associated with papulonodular skin lesions, severe arthritis and malignancy. Histopathology shows histiocytes containing abundant eosinophilic ground glass cytoplasm and multinucleated giant cells. Early recognition, age‐appropriate malignancy work‐up and treatment is important to prevent impairment of daily life activity.https://doi.org/10.1002/ccr3.7846arthritis mutilansautoimmune diseasemulticentric reticulohistiocytosisnon‐langerhans cell histiocytosispapulonodular skin lesion |
| spellingShingle | Omowunmi Ashaolu Selwyn Ng Shaun Smale Jenny Hughes Multicentric Reticulohistiocytosis–A rare and disabling disease Clinical Case Reports arthritis mutilans autoimmune disease multicentric reticulohistiocytosis non‐langerhans cell histiocytosis papulonodular skin lesion |
| title | Multicentric Reticulohistiocytosis–A rare and disabling disease |
| title_full | Multicentric Reticulohistiocytosis–A rare and disabling disease |
| title_fullStr | Multicentric Reticulohistiocytosis–A rare and disabling disease |
| title_full_unstemmed | Multicentric Reticulohistiocytosis–A rare and disabling disease |
| title_short | Multicentric Reticulohistiocytosis–A rare and disabling disease |
| title_sort | multicentric reticulohistiocytosis a rare and disabling disease |
| topic | arthritis mutilans autoimmune disease multicentric reticulohistiocytosis non‐langerhans cell histiocytosis papulonodular skin lesion |
| url | https://doi.org/10.1002/ccr3.7846 |
| work_keys_str_mv | AT omowunmiashaolu multicentricreticulohistiocytosisarareanddisablingdisease AT selwynng multicentricreticulohistiocytosisarareanddisablingdisease AT shaunsmale multicentricreticulohistiocytosisarareanddisablingdisease AT jennyhughes multicentricreticulohistiocytosisarareanddisablingdisease |