Drugging the Undruggable <i>Trypanosoma brucei</i> Monothiol Glutaredoxin 1

Trypanosoma brucei is a species of kinetoplastid causing sleeping sickness in humans and nagana in cows and horses. One of the peculiarities of this species of parasites is represented by their redox metabolism. One of the proteins involved in this redox machinery is the monothiol glutaredoxin 1 (1C...

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Bibliographic Details
Main Authors: Annagiulia Favaro, Giovanni Bolcato, Marcelo A. Comini, Stefano Moro, Massimo Bellanda, Mattia Sturlese
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/3/1276